Effect of the ordered water on protein folding: An off-lattice Go$$($)over-bar-like model study
文献类型:期刊论文
作者 | Zuo, GH ; Hu, J(胡钧) ; Fang, HP(方海平) |
刊名 | PHYSICAL REVIEW E
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出版日期 | 2009 |
卷号 | 79期号:3页码:6 |
关键词 | cellular biophysics ice molecular biophysics proteins solvent effects surface phenomena water |
ISSN号 | 1539-3755 |
通讯作者 | Fang, HP (reprint author), Fudan Univ, T Life Res Ctr, Shanghai 200433, Peoples R China |
英文摘要 | Recent experiments and numerical simulations have shown that the water molecules confined on the surfaces of some substrates, including the surfaces of cellular components in tissues and cells, form icelike ordered structures. If a protein folds in an environment with those icelike ordered water molecules, its behavior may be different from that in bulk water. Here, the effect of this ordered water environment on protein folding is studied by using an off-lattice Go $$($) over bar -like model. It is found that the ordered water environment significantly improves the native state stability and greatly speeds up the folding rate of the proteins. |
学科主题 | Physics |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000264767300113 |
公开日期 | 2012-04-11 |
源URL | [http://ir.sinap.ac.cn/handle/331007/6900] ![]() |
专题 | 上海应用物理研究所_中科院上海应用物理研究所2004-2010年 |
推荐引用方式 GB/T 7714 | Zuo, GH,Hu, J,Fang, HP. Effect of the ordered water on protein folding: An off-lattice Go$$($)over-bar-like model study[J]. PHYSICAL REVIEW E,2009,79(3):6. |
APA | Zuo, GH,Hu, J,&Fang, HP.(2009).Effect of the ordered water on protein folding: An off-lattice Go$$($)over-bar-like model study.PHYSICAL REVIEW E,79(3),6. |
MLA | Zuo, GH,et al."Effect of the ordered water on protein folding: An off-lattice Go$$($)over-bar-like model study".PHYSICAL REVIEW E 79.3(2009):6. |
入库方式: OAI收割
来源:上海应用物理研究所
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