中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Effect of the ordered water on protein folding: An off-lattice Go$$($)over-bar-like model study

文献类型:期刊论文

作者Zuo, GH ; Hu, J(胡钧) ; Fang, HP(方海平)
刊名PHYSICAL REVIEW E
出版日期2009
卷号79期号:3页码:6
关键词cellular biophysics ice molecular biophysics proteins solvent effects surface phenomena water
ISSN号1539-3755
通讯作者Fang, HP (reprint author), Fudan Univ, T Life Res Ctr, Shanghai 200433, Peoples R China
英文摘要Recent experiments and numerical simulations have shown that the water molecules confined on the surfaces of some substrates, including the surfaces of cellular components in tissues and cells, form icelike ordered structures. If a protein folds in an environment with those icelike ordered water molecules, its behavior may be different from that in bulk water. Here, the effect of this ordered water environment on protein folding is studied by using an off-lattice Go $$($) over bar -like model. It is found that the ordered water environment significantly improves the native state stability and greatly speeds up the folding rate of the proteins.
学科主题Physics
收录类别SCI
语种英语
WOS记录号WOS:000264767300113
公开日期2012-04-11
源URL[http://ir.sinap.ac.cn/handle/331007/6900]  
专题上海应用物理研究所_中科院上海应用物理研究所2004-2010年
推荐引用方式
GB/T 7714
Zuo, GH,Hu, J,Fang, HP. Effect of the ordered water on protein folding: An off-lattice Go$$($)over-bar-like model study[J]. PHYSICAL REVIEW E,2009,79(3):6.
APA Zuo, GH,Hu, J,&Fang, HP.(2009).Effect of the ordered water on protein folding: An off-lattice Go$$($)over-bar-like model study.PHYSICAL REVIEW E,79(3),6.
MLA Zuo, GH,et al."Effect of the ordered water on protein folding: An off-lattice Go$$($)over-bar-like model study".PHYSICAL REVIEW E 79.3(2009):6.

入库方式: OAI收割

来源:上海应用物理研究所

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