Protective effect of melatonin on photo-damage to lysozyme
文献类型：期刊论文
| 作者 | Zhu, HP ; Chen, SM(陈仕谋） ; Yao, S（姚思德） ; Wang, WF（王文峰） |
| 刊名 | JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
 |
| 出版日期 | 2009 |
| 卷号 | 94期号:2页码:6 |
| 关键词 | Protein Antioxidant Melatonin Photo-oxidation Spin trapping |
| ISSN号 | 1011-1344 |
| 通讯作者 | Zhu, HP (reprint author), ETH, Dept Chem & Appl Biosci, Inorgan Chem Lab, Wolfgang Pauli Str 10, CH-8093 Zurich, Switzerland |
| 英文摘要 | The behavior of melatonin in the riboflavin-sensitized photo-oxidation of lysozyme was monitored. Melatonin was found to prevent aggregation of protein and the decrease of enzyme activity induced by photo-oxidation. Electron spin resonance experiments showed that photo-oxidation of lysozyme in the presence of riboflavin resulted in formation of protein radicals, and melatonin was highly effective in reducing the formation of protein radicals. Direct evidence of melatonin's ability for quenching the triplet state of riboflavin and singlet oxygen was presented. A mechanism of the protective effect of melatonin on photo-oxidation of protein was proposed and the physiological relevance was discussed. (C) 2008 Elsevier B.V. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology; Biophysics |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000263426400008 |
| 公开日期 | 2012-04-11 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/7023]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2004-2010年 |
| 推荐引用方式 GB/T 7714 | Zhu, HP,Chen, SM,Yao, S,et al. Protective effect of melatonin on photo-damage to lysozyme[J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,2009,94(2):6. |
| APA | Zhu, HP,Chen, SM,Yao, S,&Wang, WF.(2009).Protective effect of melatonin on photo-damage to lysozyme.JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,94(2),6. |
| MLA | Zhu, HP,et al."Protective effect of melatonin on photo-damage to lysozyme".JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY 94.2(2009):6. |
入库方式： OAI收割
来源：上海应用物理研究所
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