Supramolecular Structures of Amyloid-Related Peptides in an Ambient Water Nanofilm
文献类型：期刊论文
| 作者 | Ye, Ming(叶鸣) ; Zhang, Yi(张益) ; Li, Hai(李海) ; Xie, Muyun ; Hu, Jun(胡钧) |
| 刊名 | JOURNAL OF PHYSICAL CHEMISTRY B
 |
| 出版日期 | 2010 |
| 卷号 | 114期号:48页码:7 |
| ISSN号 | 1520-6106 |
| 通讯作者 | Zhang, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China |
| 英文摘要 | An ambient water nanofilm condensed on a solid surface provides a good model system to study the self-assembling behaviors of peptides in a confined environment In this paper the self-assembly of three short amyloid-related peptides in a water nanofilm confined on a mica substrate was studied using drying microcontact printing (D-mu CP) and atomic force microscopy (AFM) The three peptides which share the same amino acid sequence but have different terminal groups were placed on mica surfaces by D-mu CP The samples were then incubated in a chamber with a controlled temperature and relative humidity (RH) in which water nanofilms were generated on the sample surfaces AFM images revealed that the peptides assembled into two kinds of supramolecular structures nanofilaments and nanosheets The peptides' terminal groups and the thickness of the water nanofilms determined the self-assembled supramolecular structures in the water nanofilm Through AFM investigation of the formation and transformation of the peptides' supramolecular structures, we conclude that the peptides self-assembly process was dominated by weak interactions, such as hydrophobic and electrostatic interactions and hydrogen bonding, between the peptide molecules the mica substrate, and the water nanofilm On the basis of these results, a model that describes the peptide arrangement in the confined water nanofilm is proposed This study reveals the complicated interactions of the peptides at an interface, which may be a general mechanism in vivo because water confinement around biomolecules and membranes is a universal phenomenon |
| 学科主题 | Chemistry |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000284738800004 |
| 公开日期 | 2012-04-11 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/7070]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2004-2010年 |
| 推荐引用方式 GB/T 7714 | Ye, Ming,Zhang, Yi,Li, Hai,et al. Supramolecular Structures of Amyloid-Related Peptides in an Ambient Water Nanofilm[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2010,114(48):7. |
| APA | Ye, Ming,Zhang, Yi,Li, Hai,Xie, Muyun,&Hu, Jun.(2010).Supramolecular Structures of Amyloid-Related Peptides in an Ambient Water Nanofilm.JOURNAL OF PHYSICAL CHEMISTRY B,114(48),7. |
| MLA | Ye, Ming,et al."Supramolecular Structures of Amyloid-Related Peptides in an Ambient Water Nanofilm".JOURNAL OF PHYSICAL CHEMISTRY B 114.48(2010):7. |
入库方式： OAI收割
来源：上海应用物理研究所
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