Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy
文献类型:期刊论文
作者 | Liu NN ; Peng B ; Lin YA ; Su ZH ; Niu ZW ; Wang QA ; Zhang WK ; Li HB ; Shen JC |
刊名 | journal of the american chemical society
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出版日期 | 2010 |
卷号 | 132期号:32页码:11036-11038 |
关键词 | DNA-MOLECULES RESOLUTION AFM MICROSCOPY PROTEIN TITIN MECHANOCHEMISTRY PARTICLE EVENTS |
ISSN号 | 0002-7863 |
通讯作者 | zhang wk |
中文摘要 | rna-coat protein interactions in intact tobacco mosaic virus have been investigated for the first time directly on the single-molecule level by pulling the genetic rna step by step out of the helical groove formed by its protein coat. the effects of pulling speed and ph on rna-protein interactions are presented. in addition, the rebinding behavior of the detached rna with the protein coat is discussed. our results demonstrate the possibility of studying nucleic acid-protein interactions in more complicated systems using afm-based single-molecule force spectroscopy. |
收录类别 | SCI收录期刊论文 |
语种 | 英语 |
WOS记录号 | WOS:000280861300031 |
公开日期 | 2012-04-26 |
源URL | [http://ir.ciac.jl.cn/handle/322003/43536] ![]() |
专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
推荐引用方式 GB/T 7714 | Liu NN,Peng B,Lin YA,et al. Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy[J]. journal of the american chemical society,2010,132(32):11036-11038. |
APA | Liu NN.,Peng B.,Lin YA.,Su ZH.,Niu ZW.,...&Shen JC.(2010).Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy.journal of the american chemical society,132(32),11036-11038. |
MLA | Liu NN,et al."Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy".journal of the american chemical society 132.32(2010):11036-11038. |
入库方式: OAI收割
来源:长春应用化学研究所
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