Au NPs-enhanced surface plasmon resonance for sensitive detection of mercury(II) ions
文献类型：期刊论文
| 作者 | Wang L ; Li T ; Du Y ; Chen CG ; Li L ; Zhou M ; Dong SJ |
| 刊名 | biosensors & bioelectronics
 |
| 出版日期 | 2010 |
| 卷号 | 25期号:12页码:2622-2626 |
| 关键词 | HEAVY-METAL IONS DNA HYBRIDIZATION ULTRASENSITIVE DETECTION COLORIMETRIC DETECTION AQUEOUS-SOLUTION GOLD SURFACES BASE-PAIRS SPECTROSCOPY HG2+ SENSOR |
| ISSN号 | 0956-5663 |
| 通讯作者 | dong sj |
| 中文摘要 | we reported a sensitive surface plasmon resonance (spr) sensor for the detection of hg2+ in aqueous solution by using a thymine (t)-rich, mercury-specific oligonucleotide (mso) probe and gold nanoparticles (au nps)-based signal amplification. the mso probe was first immobilized on gold film through formation of au-s bond between dna and gold film. in the presence of hg2+, the mso probe captured free hg2+ in aqueous media via the hg2+-mediated coordination of t-hg2+-t base pairs. this direct immobilization strategy led to a detection limit of 0.3 mu m of hg2+. in order to improve the sensitivity, part complementary dna (pcs)-modified au nps labels were employed to amplify spr signals. we demonstrated that this au nps-based sensing strategy resulted in a detection limit down to 5 nm of hg2+, brings about an amplification factor of two orders of magnitude. this au nps-based hg2+ sensor also exhibited excellent selectivity over a spectrum of interference metal ions. taking advantage of the high amplifying characteristic of au nps and the specificity of mso to hg2+ recognition, we developed here a spr sensor for specific hg2+ detection with high sensitivity. (c) 2010 elsevier b.v. all rights reserved. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000279538700012 |
| 公开日期 | 2012-04-26 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/43615]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wang L,Li T,Du Y,et al. Au NPs-enhanced surface plasmon resonance for sensitive detection of mercury(II) ions[J]. biosensors & bioelectronics,2010,25(12):2622-2626. |
| APA | Wang L.,Li T.,Du Y.,Chen CG.,Li L.,...&Dong SJ.(2010).Au NPs-enhanced surface plasmon resonance for sensitive detection of mercury(II) ions.biosensors & bioelectronics,25(12),2622-2626. |
| MLA | Wang L,et al."Au NPs-enhanced surface plasmon resonance for sensitive detection of mercury(II) ions".biosensors & bioelectronics 25.12(2010):2622-2626. |
入库方式： OAI收割
来源：长春应用化学研究所
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