Efficient one-pot synthesis of substituted pyridines through multicomponent reaction
文献类型：期刊论文
| 作者 | Xin X ; Wang Y ; Kumar S ; Liu X ; Lin YJ ; Dong DW |
| 刊名 | organic & biomolecular chemistry
 |
| 出版日期 | 2010 |
| 卷号 | 8期号:13页码:3078-3082 |
| 关键词 | ALPHA-CARBAMOYL KETENE-S 1 S-ACETALS VILSMEIER-HAACK REACTION 3-DICARBONYL COMPOUNDS CYCLIZATION REACTIONS 3-COMPONENT SYNTHESIS 5C+1N ANNULATION IONIC LIQUID ONE-STEP DERIVATIVES FACILE |
| ISSN号 | 1477-0520 |
| 通讯作者 | dong dw |
| 中文摘要 | a facile and convenient synthesis of substituted pyridines has been developed via a one-pot multicomponent reaction of easily available 1,3-dicarbonyl compounds, aromatic aldehydes, malononitrile and alcohol in the presence of naoh under mild conditions. a series of functionalized pyridines were thus obtained by this multicomponent reaction, in which four new bonds were formed in a highly chemo- and regioselective manner, and alcohol played dual roles as both reactant and reaction medium. particularly valuable features of this protocol including mild conditions, simple execution, broad substrate scope, and good yields of products make it an efficient and promising synthetic strategy to build pyridine skeleton. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000278824700028 |
| 公开日期 | 2012-04-26 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/43649]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Xin X,Wang Y,Kumar S,et al. Efficient one-pot synthesis of substituted pyridines through multicomponent reaction[J]. organic & biomolecular chemistry,2010,8(13):3078-3082. |
| APA | Xin X,Wang Y,Kumar S,Liu X,Lin YJ,&Dong DW.(2010).Efficient one-pot synthesis of substituted pyridines through multicomponent reaction.organic & biomolecular chemistry,8(13),3078-3082. |
| MLA | Xin X,et al."Efficient one-pot synthesis of substituted pyridines through multicomponent reaction".organic & biomolecular chemistry 8.13(2010):3078-3082. |
入库方式： OAI收割
来源：长春应用化学研究所
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