Improved biological performance of low modulus Ti-24Nb-4Zr-7.9Sn implants due to surface modification by anodic oxidation
文献类型：期刊论文
| 作者 | Y. Gao ; B. Gao ; R. Wang ; J. Wu ; L. J. Zhang ; Y. L. Hao ; X. J. Tao |
| 刊名 | Applied Surface Science
 |
| 出版日期 | 2009 |
| 卷号 | 255期号:9页码:5009-5015 |
| 关键词 | Titanium alloy Anodic oxidation Biocompatibility Osteoblast Osseointegration in-vitro titanium surfaces bone response osteoblast calcium behavior alloy topography adsorption attachment |
| ISSN号 | 0169-4332 |
| 中文摘要 | Dental implants are usually made from commercially pure titanium or titanium alloys. The purpose of this study was to evaluate the influence of surface treatment to low modulus Ti-24Nb-4Zr-7.9Sn (TNZS) on cell and bone responses. The TNZS alloy samples were modified using anodic oxidation (AD). Surface oxide properties were characterized by using various surface analytic techniques, involving scanning electron microscopy (SEM) equipped with energy dispersive spectrometer (EDS), X-ray diffractometry (XRD) and surface profilometer. During the AD treatment, porous titanium oxide layer was formed and Ca ions were incorporated into the oxide layer. The viability and morphology of osteoblasts on Ca-incorporated TNZS were studied. The bone responses of Ca-incorporated TNZS were evaluated by pull-out tests and morphological analysis after implantation in rabbit tibiae. The non-treated Ti and TNZS samples were used as the control. Significant increases in cell viability and pull-out forces (p < 0.05) were observed for Ca-incorporated TNZS implants compared with those for the control groups. Porous structures supplied positive guidance cues for osteoblasts to attach. The enhanced cell and bone responses to Ca-incorporated TNZS implants could be explained by the surface chemistry and microtopography. (c) 2009 Elsevier B.V. All rights reserved. |
| 原文出处 | |
| 公开日期 | 2012-04-13 |
| 源URL | [http://210.72.142.130/handle/321006/31929]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 推荐引用方式 GB/T 7714 | Y. Gao,B. Gao,R. Wang,et al. Improved biological performance of low modulus Ti-24Nb-4Zr-7.9Sn implants due to surface modification by anodic oxidation[J]. Applied Surface Science,2009,255(9):5009-5015. |
| APA | Y. Gao.,B. Gao.,R. Wang.,J. Wu.,L. J. Zhang.,...&X. J. Tao.(2009).Improved biological performance of low modulus Ti-24Nb-4Zr-7.9Sn implants due to surface modification by anodic oxidation.Applied Surface Science,255(9),5009-5015. |
| MLA | Y. Gao,et al."Improved biological performance of low modulus Ti-24Nb-4Zr-7.9Sn implants due to surface modification by anodic oxidation".Applied Surface Science 255.9(2009):5009-5015. |
入库方式： OAI收割
来源：金属研究所
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