Synthesis of Magnetic Nanobiomaterials and Its Biological Effects
文献类型：期刊论文
| 作者 | X. F. Pang ; B. Deng ; Q. Zhao |
| 刊名 | Journal of Nanoscience and Nanotechnology
 |
| 出版日期 | 2009 |
| 卷号 | 9期号:2页码:1369-1373 |
| 关键词 | Magnetic Bio-Nanomaterial Infrared Spectrum Cell Proliferation Biological Effect Synthesis |
| ISSN号 | 1533-4880 |
| 中文摘要 | Iron oxides and its hydrate nanoparticles, for example, nanoFe(3)O(4) and nanoFe(3)O(4) with hydroxyl, were synthesized by hydrothermal method, their sizes and features are evaluated by infrared spectra and Scanning Electron Microscope (SEM) etc. The dimensions of these nanoparticles produced are about 50-120 nm. In the investigation of influence of nanoFe(3)O(4) and nanoFe(3)O(4) with hydroxyl on crystalline states of amino acid molecules, their crystalline forms are different to that of pure amino acid molecules. The positions and widths of peaks of these nanoparticles in the infrared spectra of absorption are changed largely relative to that of pure amino acid molecules. From the experiments of microscope observation and infrared spectra of re-crytalline amino acids we see that the nanoFe(3)O(4) and nanoFe(3)O(4) with hydroxyl can change the structure of amino acid molecules. To study the toxicity of synthesized nanoparticles, the MTT (3-(4,5-dimethyl-thiazol 2-yl)-2,5 diphenyltetrazolium bromide) assay was used. The OD value (Optical Density) was used to calculated RGR (Relative Generation Rate) of cells, which determined the grade of cytotoxicity. The RGR of nanoparticles of iron oxide and its hydrate are about 1 to 2, which indicate that they have a lower toxicity. |
| 原文出处 | |
| 公开日期 | 2012-04-13 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/32230]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 推荐引用方式 GB/T 7714 | X. F. Pang,B. Deng,Q. Zhao. Synthesis of Magnetic Nanobiomaterials and Its Biological Effects[J]. Journal of Nanoscience and Nanotechnology,2009,9(2):1369-1373. |
| APA | X. F. Pang,B. Deng,&Q. Zhao.(2009).Synthesis of Magnetic Nanobiomaterials and Its Biological Effects.Journal of Nanoscience and Nanotechnology,9(2),1369-1373. |
| MLA | X. F. Pang,et al."Synthesis of Magnetic Nanobiomaterials and Its Biological Effects".Journal of Nanoscience and Nanotechnology 9.2(2009):1369-1373. |
入库方式： OAI收割
来源：金属研究所
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