Surface microstructure and cell biocompatibility of silicon-substituted hydroxyapatite coating on titanium substrate prepared by a biomimetic process
文献类型：期刊论文
| 作者 | E. Zhang ; C. M. Zou ; G. N. Yu |
| 刊名 | Materials Science & Engineering C-Biomimetic and Supramolecular Systems
 |
| 出版日期 | 2009 |
| 卷号 | 29期号:1页码:298-305 |
| 关键词 | Biomimetic Coating Silicon-substituted hydroxyapatite Titanium Biocompatibility calcium-phosphate coatings thin-films si-ha deposition bone dissolution apatite spectroscopy bioceramics attachment |
| ISSN号 | 0928-4931 |
| 中文摘要 | Silicon-substituted hydroxyapatite (Si-HA) coatings with 0.14 to 1.14 at.% Si on pure titanium were prepared by a biomimetic process. The microstructure characterization and the cell compatibility of the Si-HA coatings were studied in comparison with that of hydroxyapatite (HA) coating prepared in the same way, The prepared Si-HA coatings and HA coating were only partially crystallized or in nano-scaled crystals. The introduction of Si element in HA significantly reduced P and Ca content, but densified the coating. The atom ratio of Ca to (P+Si) in the Si-HA coatings was in a range of 1.61-1.73, increasing slightly with an increase in the Si content. FTIR results displayed that Si entered HA in a form of SiO(4) unit by substituting for PO(4) unit. The cell attachment test showed that the HA and Si-HA coatings exhibited better cell response than the uncoated titanium, but no difference was observed in the cell response between the HA coating and the Si-HA coatings. Both the HA coating and the Si-HA coatings demonstrated a significantly higher cell growth rate than the uncoated pure titanium (p < 0.05) in all incubation periods while the Si-HA coating exhibited a significantly higher cell growth rate than the HA coating (p < 0.05). Si-HA with 0.42 at.% Si presented the best cell biocompatibility in all of the incubation periods. It was suggested that the synthesis mode of HA and Si-HA coatings in a simulated body environment in the biomimetic process contribute significantly to good cell biocompatibility. (c) 2008 Elsevier B.V. All rights reserved. |
| 原文出处 | |
| 公开日期 | 2012-04-13 |
| 源URL | [http://210.72.142.130/handle/321006/32526]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 推荐引用方式 GB/T 7714 | E. Zhang,C. M. Zou,G. N. Yu. Surface microstructure and cell biocompatibility of silicon-substituted hydroxyapatite coating on titanium substrate prepared by a biomimetic process[J]. Materials Science & Engineering C-Biomimetic and Supramolecular Systems,2009,29(1):298-305. |
| APA | E. Zhang,C. M. Zou,&G. N. Yu.(2009).Surface microstructure and cell biocompatibility of silicon-substituted hydroxyapatite coating on titanium substrate prepared by a biomimetic process.Materials Science & Engineering C-Biomimetic and Supramolecular Systems,29(1),298-305. |
| MLA | E. Zhang,et al."Surface microstructure and cell biocompatibility of silicon-substituted hydroxyapatite coating on titanium substrate prepared by a biomimetic process".Materials Science & Engineering C-Biomimetic and Supramolecular Systems 29.1(2009):298-305. |
入库方式： OAI收割
来源：金属研究所
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