Fibroblast adhesion and proliferation on a new beta type Ti-39Nb-13Ta-4.6Zr alloy for biomedical application
文献类型：期刊论文
| 作者 | Y. K. Zhao ; Y. Yao ; W. X. Liu ; C. Y. Zheng ; S. J. Li |
| 刊名 | Journal of Materials Science & Technology
 |
| 出版日期 | 2006 |
| 卷号 | 22期号:2页码:205-210 |
| 关键词 | biomaterials titanium alloys fibroblast adhesion proliferation surface roughness nb-ta-zr osteoblast-like cells surface-roughness titanium surfaces epithelial-cells ti-6al-4v |
| ISSN号 | 1005-0302 |
| 中文摘要 | Cell attachment and spreading on Ti-based alloy surfaces is a major parameter in implant technology. Ti39Nb-13Ta-4.6Zr alloy is a new beta type Ti alloy developed for biomedical application. This alloy has low modulus and high strength, which indicates that it can be used for medical purposes such as surgical implants. To evaluate the biocompatibility and effects of the surface morphology of Ti-39Nb-13Ta-4.6Zr on the cellular behaviour, the adhesion and proliferation of rat gingival fibroblasts were studied with substrates having different surface roughness and the results were also compared with commercial pure titanium and Ti-6Al-4V. The results indicate that fibroblast shows similar adhesion and proliferation on the smooth surfaces of commercial pure titanium (Cp Ti), Ti-39Nb-13Ta-4.6Zr, and Ti-6Al-4V, suggesting that Ti-39Nb-13Ta-4.6Zr has similar biocompatibility to Cp Ti and Ti-6Al-4V. The fibroblast adhesion and spreading was lower on rough surfaces of Cp Ti, Ti-39Nb-13Ta-4.6Zr and Ti-6Al-4V than on smooth ones. Surface roughness appeared to be a dominant factor that determines the fibroblast adhesion and proliferation. |
| 原文出处 | |
| 公开日期 | 2012-04-14 |
| 源URL | [http://ir.imr.ac.cn/handle/321006/34747]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 推荐引用方式 GB/T 7714 | Y. K. Zhao,Y. Yao,W. X. Liu,et al. Fibroblast adhesion and proliferation on a new beta type Ti-39Nb-13Ta-4.6Zr alloy for biomedical application[J]. Journal of Materials Science & Technology,2006,22(2):205-210. |
| APA | Y. K. Zhao,Y. Yao,W. X. Liu,C. Y. Zheng,&S. J. Li.(2006).Fibroblast adhesion and proliferation on a new beta type Ti-39Nb-13Ta-4.6Zr alloy for biomedical application.Journal of Materials Science & Technology,22(2),205-210. |
| MLA | Y. K. Zhao,et al."Fibroblast adhesion and proliferation on a new beta type Ti-39Nb-13Ta-4.6Zr alloy for biomedical application".Journal of Materials Science & Technology 22.2(2006):205-210. |
入库方式： OAI收割
来源：金属研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。