Evaluation of angiotensin I-converting enzyme (ACE) inhibitory activities of hydrolysates generated from byproducts of freshwater clam
文献类型：期刊论文
| 作者 | Sun, Yuanxia1; Hayakawa, Shigeru2; Ogawa, Masahiro2; Naknukool, Supaporn2; Guan, Yupin1; Matsumoto, Yoshiyuki2 |
| 刊名 | FOOD SCIENCE AND BIOTECHNOLOGY
 |
| 出版日期 | 2011-04-01 |
| 卷号 | 20期号:2页码:303-310 |
| 关键词 | angiotensin I-converting enzyme (ACE) inhibitor bioactive peptide hydrolysis dried mantle freshwater clam |
| 英文摘要 | Solid wastes of freshwater clam in food processing, including mainly mantle, were used as a raw material for the recovery of bioactive peptides related to angiotensin I-converting enzyme (ACE) inhibitor. Among the primary hydrolysates of dried mantle (DM), the peptides corresponding to hydrolysates using 2 crude peptidases exhibited a strong ACE inhibitory activity (IC(50), 0.23 mg/mL), and recovery efficiency of soluble materials and their protein content were considerably large with 42.65% and 468.6 mg/g, respectively. The ACE inhibitory activity of all secondary hydrolysates digested by pepsin and trypsin was significantly increased as compared to primary hydrolysates. Furthermore, the peptic secondary hydrolysates were fractionated by gel filtration and reverse phase-HPLC (RP-HPLC) and characterized by matrix-assisted laser desorption-ionization time of flight/mass spectrometry (MALDI-TOF/MS). These peptides with molecular weight of less than 1 kDa possessed the stronger ACE inhibitory effect, and their inhibitory pattern was found to be competitive. The results showed that the DM hydoplysates might be utilized as a rich source of bioactive peptide. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Food Science & Technology |
| 研究领域[WOS] | Food Science & Technology |
| 关键词[WOS] | SPECTROPHOTOMETRIC ASSAY ; FRAME PROTEIN ; PEPTIDES ; MUSCLE ; COLLAGEN ; SCALES ; MILK ; SKIN |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000290039500003 |
| 公开日期 | 2011-08-01 |
| 源URL | [http://localhost/handle/0/57]  |
| 专题 | 天津工业生物技术研究所_功能糖与天然活性物质研究组 孙媛霞 _期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin 300308, Seoul, Peoples R China 2.Kagawa Univ, Dept Biochem & Food Sci, Kagawa 7610795, Japan |
| 推荐引用方式 GB/T 7714 | Sun, Yuanxia,Hayakawa, Shigeru,Ogawa, Masahiro,et al. Evaluation of angiotensin I-converting enzyme (ACE) inhibitory activities of hydrolysates generated from byproducts of freshwater clam[J]. FOOD SCIENCE AND BIOTECHNOLOGY,2011,20(2):303-310. |
| APA | Sun, Yuanxia,Hayakawa, Shigeru,Ogawa, Masahiro,Naknukool, Supaporn,Guan, Yupin,&Matsumoto, Yoshiyuki.(2011).Evaluation of angiotensin I-converting enzyme (ACE) inhibitory activities of hydrolysates generated from byproducts of freshwater clam.FOOD SCIENCE AND BIOTECHNOLOGY,20(2),303-310. |
| MLA | Sun, Yuanxia,et al."Evaluation of angiotensin I-converting enzyme (ACE) inhibitory activities of hydrolysates generated from byproducts of freshwater clam".FOOD SCIENCE AND BIOTECHNOLOGY 20.2(2011):303-310. |
入库方式： OAI收割
来源：天津工业生物技术研究所
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