Antitumor activities of different fractions of polysaccharide purified from Ornithogalum caudatum Ait
文献类型：期刊论文
| 作者 | Chen RZ ; Meng FL ; Liu ZQ ; Chen RP ; Zhang M |
| 刊名 | carbohydrate polymers
 |
| 出版日期 | 2010 |
| 卷号 | 80期号:3页码:845-851 |
| 关键词 | WATER-SOLUBLE POLYSACCHARIDES ANTIOXIDANT ACTIVITIES DIETARY FIBER DEGRADATION SINENSIS |
| ISSN号 | 0144-8617 |
| 通讯作者 | liu zq |
| 中文摘要 | four water-soluble polysaccharide fractions (ocap-2-1, ocap-2-2, ocap-3-1 and ocap-3-3) extracted from the ornithogalum caudatum ait, were obtained by deae fast flow sepharose anion-exchange, and sephadex g-75 gel-permeation chromatography. the monosaccharide components of four polysaccharides were characterized by gas chromatography (gc), and the majority of the monosaccharide components were glucose (30-42.5%) and galactose (23-29%), with low levels of arabinose (6-14%), mannose (2-9%), xylose (4-6%), glucuronic acid (1.0-7.5%), galactose acid (1-6%). the high-performance gel-permeation chromatography (hpgpc) analysis showed that the average molecular weight (m-w) of four polysaccharides were approximately 102.1, 62.3, 46.4 and 22.8 kda, respectively. the protein contents of four fractions were 2.13%, 2.82%, 3.45% and 3.97%, respectively. all polysaccharide fractions exhibited significantly higher antitumor activity against solid tumor sarcoma 180 in vivo than did a blank control. fractions ocap-2-2, ocap-3-1 and ocap-3-2 significantly inhibited the growth of k562 cells in vitro. results of these studies demonstrated that the polysaccharide had a potential application as natural antitumor drugs. crown copyright (c) 2010 published by elsevier ltd. all rights reserved. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000276987800031 |
| 公开日期 | 2012-06-06 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/43769]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Chen RZ,Meng FL,Liu ZQ,et al. Antitumor activities of different fractions of polysaccharide purified from Ornithogalum caudatum Ait[J]. carbohydrate polymers,2010,80(3):845-851. |
| APA | Chen RZ,Meng FL,Liu ZQ,Chen RP,&Zhang M.(2010).Antitumor activities of different fractions of polysaccharide purified from Ornithogalum caudatum Ait.carbohydrate polymers,80(3),845-851. |
| MLA | Chen RZ,et al."Antitumor activities of different fractions of polysaccharide purified from Ornithogalum caudatum Ait".carbohydrate polymers 80.3(2010):845-851. |
入库方式： OAI收割
来源：长春应用化学研究所
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