Covalently Attached, Silver-Doped Poly(vinyl alcohol) Hydrogel Films on Poly(L-lactic acid)
文献类型：期刊论文
| 作者 | Zan XJ ; Kozlov M ; McCarthy TJ ; Su ZH |
| 刊名 | biomacromolecules
 |
| 出版日期 | 2010 |
| 卷号 | 11期号:4页码:1082-1088 |
| 关键词 | ANTIBACTERIAL PROPERTIES BIODEGRADABLE POLYMERS INFRARED-SPECTROSCOPY POLY(ETHYLENE GLYCOL) SURFACE MODIFICATION PROTEIN ADSORPTION DEGRADATION NANOPARTICLES RESISTANCE BONE |
| ISSN号 | 1525-7797 |
| 通讯作者 | su zh |
| 中文摘要 | covalently attached, soft poly(vinyl alcohol) (pva) hydrogel films containing silver particles were prepared on solid biodegradable poly(l-lactic acid) (plla) samples by a multistep procedure involving oxygen plasma treatment, uv-initiated graft polymerization, and chemical grafting methods. the modification steps were followed and verified using attenuated total reflection infrared spectroscopy and x-ray photoelectron spectroscopy. 2-hydroxyethyl methacrylate (hema) was graft polymerized from the surface of oxygen plasma-treated plla film samples and the alcohol functionality in the grafted polyhema chains was oxidized using pyridinium dichromate to obtain an aldehyde-rich surface. pva was then grafted onto this surface using acid catalysis (acetal formation). the "freeze/thaw method" was used to form a pva hydrogel layer that incorporated the covalently grafted pva chains in the physically cross-linked gel. this composite film (plla-pva(gel)) was doped with silver ions, which were reduced to silver using nabh4. scanning electron microscopy of cross sections of plla-pva(gel) indicates robust attachment of the pva hydrogel layer to the plla film. plla-pva(gel/ag(0)) film samples exhibit both antibacterial and reduced cell adhesion properties due to the antibacterial properties of silver nanoparticles and high water content, respectively. this method provides a route to mechanically sound biodegradable materials with tunable soft material surface properties. potential applications in tissue engineering and biomedical devices are envisioned. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000276557300033 |
| 公开日期 | 2012-06-07 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/43809]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zan XJ,Kozlov M,McCarthy TJ,et al. Covalently Attached, Silver-Doped Poly(vinyl alcohol) Hydrogel Films on Poly(L-lactic acid)[J]. biomacromolecules,2010,11(4):1082-1088. |
| APA | Zan XJ,Kozlov M,McCarthy TJ,&Su ZH.(2010).Covalently Attached, Silver-Doped Poly(vinyl alcohol) Hydrogel Films on Poly(L-lactic acid).biomacromolecules,11(4),1082-1088. |
| MLA | Zan XJ,et al."Covalently Attached, Silver-Doped Poly(vinyl alcohol) Hydrogel Films on Poly(L-lactic acid)".biomacromolecules 11.4(2010):1082-1088. |
入库方式： OAI收割
来源：长春应用化学研究所
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