Self-activated luminescent and mesoporous strontium hydroxyapatite nanorods for drug delivery
文献类型：期刊论文
| 作者 | Zhang CM ; Li CX ; Huang SS ; Hou ZY ; Cheng ZY ; Yang PP ; Peng C ; Lin J |
| 刊名 | biomaterials
 |
| 出版日期 | 2010 |
| 卷号 | 31期号:12页码:3374-3383 |
| 关键词 | SILICA NANOPARTICLES CONTROLLED-RELEASE QUANTUM DOTS HUMAN-CELLS SYSTEM SHELL CORE COMPOSITES CARRIER FUNCTIONALIZATION |
| ISSN号 | 0142-9612 |
| 通讯作者 | lin j |
| 中文摘要 | multifunctional strontium hydroxyapatite (srhap) nanorods with luminescent and mesoporous properties have been successfully synthesized by a hydrothermal method. sem and tem images indicate that the mesoporous srhap samples consist of monodiperse nanorods with lengths of 120-150 nm, diameters of around 20 nm, and the mesopore size of 3-5 nm. the as-obtained srhap nanorods show an intense bright blue emission (centered at 432 nm, lifetime 11.6 ns, quantum efficiency: 22%), which might arise from co2 center dot(-) radical impurities in the crystal lattice under long-wavelength uv-light irradiation. furthermore, the amount of trisodium citrate has an obvious impact on the particle size and the luminescence properties of the products, respectively. the drug storage/release test indicates that the luminescent srhap nanorods show a drug loading and controlled release properties for ibuprofen (ibu). additionally, the emission intensity of srhap in the drug carrier system increases with the cumulative released amount of ibu, making the drug release might be easily tracked and monitored by the change of the luminescence intensity. this luminescent material may be potentially applied in the drug delivery and disease therapy fields. (c) 2010 elsevier ltd. all rights reserved. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000276126000028 |
| 公开日期 | 2012-06-07 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/43825]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zhang CM,Li CX,Huang SS,et al. Self-activated luminescent and mesoporous strontium hydroxyapatite nanorods for drug delivery[J]. biomaterials,2010,31(12):3374-3383. |
| APA | Zhang CM.,Li CX.,Huang SS.,Hou ZY.,Cheng ZY.,...&Lin J.(2010).Self-activated luminescent and mesoporous strontium hydroxyapatite nanorods for drug delivery.biomaterials,31(12),3374-3383. |
| MLA | Zhang CM,et al."Self-activated luminescent and mesoporous strontium hydroxyapatite nanorods for drug delivery".biomaterials 31.12(2010):3374-3383. |
入库方式： OAI收割
来源：长春应用化学研究所
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