Rapid Profiling of Alkaloids in Several Medicinal Herbs by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry
文献类型：期刊论文
| 作者 | Lu L ; Yue H ; Song FR ; Tsao R ; Liu ZQ ; Liu SY |
| 刊名 | chemical research in chinese universities
 |
| 出版日期 | 2010 |
| 卷号 | 26期号:1页码:11-16 |
| 关键词 | DIESTER-DITERPENOID ALKALOIDS ACONITUM L. CHINA TIME |
| ISSN号 | 1005-9040 |
| 通讯作者 | liu zq |
| 中文摘要 | a simple method was developed for rapid and direct profiling of alkaloids in medical herbs via matrix-assisted laser desorption/ionization time-of-flight mass spectrometry(maldi-tof ms). the dry herbs were first ground to powder and passed through a stainless steel sieve, mixed with the matrix solution to form a homogeneous suspension, which was then directly applied to maldi analysis. several matrices were investigated and 2,5-dihydroxybenzoic acid(dhb) was chosen as the optimized one, and the particle with small size was found to favor the analysis. using this method, the profiles of alkaloids in several medical herbs were readily obtained, and the toxicities of crude and processed radix aconiti lateralis preparata were compared via the relative intensities of the peaks of the corresponding toxic components shown in their maldi spectra. this method therefore provides a rapid and reliable protocol for obtaining profiles of alkaloids in medical herbs by using maldi-tof ms. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000275045500004 |
| 公开日期 | 2012-06-07 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/43892]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Lu L,Yue H,Song FR,et al. Rapid Profiling of Alkaloids in Several Medicinal Herbs by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry[J]. chemical research in chinese universities,2010,26(1):11-16. |
| APA | Lu L,Yue H,Song FR,Tsao R,Liu ZQ,&Liu SY.(2010).Rapid Profiling of Alkaloids in Several Medicinal Herbs by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry.chemical research in chinese universities,26(1),11-16. |
| MLA | Lu L,et al."Rapid Profiling of Alkaloids in Several Medicinal Herbs by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry".chemical research in chinese universities 26.1(2010):11-16. |
入库方式： OAI收割
来源：长春应用化学研究所
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