Photodynamic Therapy of Cancer Cells with Methanesulfonate Salts of 5-Aminolevulinic Acid and Its Derivatives
文献类型：期刊论文
| 作者 | Qiu XP ; Kosobe T ; Kawashima N |
| 刊名 | chemical research in chinese universities
 |
| 出版日期 | 2010 |
| 卷号 | 26期号:1页码:66-69 |
| 关键词 | IN-VITRO AMINOLEVULINIC-ACID SKIN HEXYLESTER VIVO BIODISTRIBUTION METHYLESTER PENETRATION CARCINOMA KINETICS |
| ISSN号 | 1005-9040 |
| 通讯作者 | qiu xp |
| 中文摘要 | a series of 5-aminolevulinic acid and its alkylester methanesulfonates was exploited to photodynamic therapy(pdt) of human lymphocytic cells, u-937 in vitro. the pdt efficiency is influenced by the concentration and incubation time. generally, for ala and its alkylester methanesulfonates, the cell survival rate decreases and the accumulation ability of ppix increases with the concentration and incubation time. we found that the longer carbon chain methanesulfonates(c5-s, c6-s, c8-s) exhibit better pdt effect than ala methanesulfonate. this possibly provides a promising route to the clinical application of ppix-mediated pdt to cancer cell. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000275045500014 |
| 公开日期 | 2012-06-07 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/43893]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Qiu XP,Kosobe T,Kawashima N. Photodynamic Therapy of Cancer Cells with Methanesulfonate Salts of 5-Aminolevulinic Acid and Its Derivatives[J]. chemical research in chinese universities,2010,26(1):66-69. |
| APA | Qiu XP,Kosobe T,&Kawashima N.(2010).Photodynamic Therapy of Cancer Cells with Methanesulfonate Salts of 5-Aminolevulinic Acid and Its Derivatives.chemical research in chinese universities,26(1),66-69. |
| MLA | Qiu XP,et al."Photodynamic Therapy of Cancer Cells with Methanesulfonate Salts of 5-Aminolevulinic Acid and Its Derivatives".chemical research in chinese universities 26.1(2010):66-69. |
入库方式： OAI收割
来源：长春应用化学研究所
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