Oligonucleotide stabilized silver nanoclusters as fluorescence probe for drug-DNA interaction investigation
文献类型:期刊论文
作者 | Yuan JP ; Guo WW ; Wang EK |
刊名 | analytica chimica acta |
出版日期 | 2011 |
卷号 | 706期号:2页码:338-342 |
ISSN号 | 0003-2670 |
关键词 | SEQUENCE SPECIFICITY AG NANOCLUSTERS HOECHST 33258 QUANTUM DOTS BINDING QUINACRINE DAUNOMYCIN ACID BENZOQUINONES FLUOROPHORES |
通讯作者 | wang ek |
中文摘要 | in this work, oligonucleotide stabilized silver nanoclusters as novel fluorescent probes were successfully utilized for the drug-dna interaction study. silver nanoclusters were proved to be sensitive probes for the drugs investigated (including of two kinds of intercalators, daunorubicin and quinacrine, as well as a non-intercalating binder bisbenzimide h 33258), as the detection limits at 10(-8) mol l(-1) level of studied drugs can be achieved. the interactions of drugs and calf thymus dna were investigated using non-linear fit analysis, and the binding constants as well as binding site sizes were obtained. as biocompatible materials, silver nanoclusters are promising in the chemical especially biochemical analysis fields. (c) 2011 elsevier b.v. all rights reserved. |
收录类别 | SCI收录期刊论文 |
语种 | 英语 |
WOS记录号 | WOS:000297184600018 |
公开日期 | 2012-06-08 |
源URL | [http://ir.ciac.jl.cn/handle/322003/44228] |
专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
推荐引用方式 GB/T 7714 | Yuan JP,Guo WW,Wang EK. Oligonucleotide stabilized silver nanoclusters as fluorescence probe for drug-DNA interaction investigation[J]. analytica chimica acta,2011,706(2):338-342. |
APA | Yuan JP,Guo WW,&Wang EK.(2011).Oligonucleotide stabilized silver nanoclusters as fluorescence probe for drug-DNA interaction investigation.analytica chimica acta,706(2),338-342. |
MLA | Yuan JP,et al."Oligonucleotide stabilized silver nanoclusters as fluorescence probe for drug-DNA interaction investigation".analytica chimica acta 706.2(2011):338-342. |
入库方式: OAI收割
来源:长春应用化学研究所
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