中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Oligonucleotide stabilized silver nanoclusters as fluorescence probe for drug-DNA interaction investigation

文献类型:期刊论文

作者Yuan JP ; Guo WW ; Wang EK
刊名analytica chimica acta
出版日期2011
卷号706期号:2页码:338-342
ISSN号0003-2670
关键词SEQUENCE SPECIFICITY AG NANOCLUSTERS HOECHST 33258 QUANTUM DOTS BINDING QUINACRINE DAUNOMYCIN ACID BENZOQUINONES FLUOROPHORES
通讯作者wang ek
中文摘要in this work, oligonucleotide stabilized silver nanoclusters as novel fluorescent probes were successfully utilized for the drug-dna interaction study. silver nanoclusters were proved to be sensitive probes for the drugs investigated (including of two kinds of intercalators, daunorubicin and quinacrine, as well as a non-intercalating binder bisbenzimide h 33258), as the detection limits at 10(-8) mol l(-1) level of studied drugs can be achieved. the interactions of drugs and calf thymus dna were investigated using non-linear fit analysis, and the binding constants as well as binding site sizes were obtained. as biocompatible materials, silver nanoclusters are promising in the chemical especially biochemical analysis fields. (c) 2011 elsevier b.v. all rights reserved.
收录类别SCI收录期刊论文
语种英语
WOS记录号WOS:000297184600018
公开日期2012-06-08
源URL[http://ir.ciac.jl.cn/handle/322003/44228]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
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GB/T 7714
Yuan JP,Guo WW,Wang EK. Oligonucleotide stabilized silver nanoclusters as fluorescence probe for drug-DNA interaction investigation[J]. analytica chimica acta,2011,706(2):338-342.
APA Yuan JP,Guo WW,&Wang EK.(2011).Oligonucleotide stabilized silver nanoclusters as fluorescence probe for drug-DNA interaction investigation.analytica chimica acta,706(2),338-342.
MLA Yuan JP,et al."Oligonucleotide stabilized silver nanoclusters as fluorescence probe for drug-DNA interaction investigation".analytica chimica acta 706.2(2011):338-342.

入库方式: OAI收割

来源:长春应用化学研究所

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