Aptamer-based colorimetric biosensing of dopamine using unmodified gold nanoparticles
文献类型：期刊论文
| 作者 | Zheng Y ; Wang Y ; Yang XR |
| 刊名 | sensors and actuators b-chemical
 |
| 出版日期 | 2011 |
| 卷号 | 156期号:1页码:95-99 |
| 关键词 | CHEMILUMINESCENCE PROBES NEUROTRANSMITTERS ELECTROPHORESIS SEQUENCES SELECTION THROMBIN BINDING GROWTH SENSOR |
| ISSN号 | 0925-4005 |
| 通讯作者 | yang xr |
| 中文摘要 | a simple, sensitive and selective colorimetric biosensor for the detection of dopamine (da) was demonstrated with a 58-mer dopamine-binding aptamer (dba) as recognition element and unmodified gold nanoparticles (aunps) as probes. upon the addition of da, the conformation of dba would change from a random coil structure to a rigid tertiary structure like a pocket and this change has been demonstrated by circular dichroism spectroscopic experiments. besides, the conformational change of dba could facilitate salt-induced aunp aggregation and lead to the color change of aunps from red to blue. the calibration modeling showed that the analytical linear range covered from 5.4 x 10(-7) m to 5.4 x 10(-6) m and the corresponding limit of detection clod) was 3.6x 10(-7) m. some common interferents such as 3,4-dihydroxyphenylalanine (dopa), catechol, epinephrine (ep), 3.4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), and ascorbic acid (aa) showed no or just a little interference in the determination of da. (c) 2011 elsevier b.v. all rights reserved. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000292058200013 |
| 公开日期 | 2012-06-08 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/44411]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zheng Y,Wang Y,Yang XR. Aptamer-based colorimetric biosensing of dopamine using unmodified gold nanoparticles[J]. sensors and actuators b-chemical,2011,156(1):95-99. |
| APA | Zheng Y,Wang Y,&Yang XR.(2011).Aptamer-based colorimetric biosensing of dopamine using unmodified gold nanoparticles.sensors and actuators b-chemical,156(1),95-99. |
| MLA | Zheng Y,et al."Aptamer-based colorimetric biosensing of dopamine using unmodified gold nanoparticles".sensors and actuators b-chemical 156.1(2011):95-99. |
入库方式： OAI收割
来源：长春应用化学研究所
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