A simple and sensitive fluorescent sensing platform for Hg(2+) ions assay based on G-quenching
文献类型：期刊论文
| 作者 | Hu P ; Jin LH ; Zhu CZ ; Dong SJ |
| 刊名 | talanta
 |
| 出版日期 | 2011 |
| 卷号 | 85期号:1页码:713-717 |
| 关键词 | COLORIMETRIC DETECTION GOLD NANOPARTICLES MERCURY(II) IONS DNA-HAIRPINS DYES OLIGONUCLEOTIDES MOLECULES MECHANISM TRANSPORT PROBES |
| ISSN号 | 0039-9140 |
| 通讯作者 | dong sj |
| 中文摘要 | in this work, a novel fluorescence biosensor was demonstrated for detection of hg(2+) ions with relatively high selectivity and sensitivity. the sensing scheme was based on g-quenching induced by hg(2+) ions. in the presence of hg(2+) ions, the single-stranded signal probe which has carboxylfluorescein (fam) and guanine segment at its 5' and 3' ends, respectively, folded into duplex-like structure via the hg(2+)-mediated coordination of t-hg(2+)-t base pairs. it brought guannine segment close to the dye and caused a remarkable decrease of fluorescence signal. the sensor showed a sensitive response to hg(2+) ions in a concentration range from 0.5 to 10 mu m. and a detection limit of 0.5 nm was given. this homogeneous system required only a single-labeled oligonucleotide, operated by concise procedures, and possessed comparable sensitivity as previous approaches. furthermore, the sensor exhibits a great perspective for future practical applications. (c) 2011 elsevier b.v. all rights reserved. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| 公开日期 | 2012-06-08 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/44466]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Hu P,Jin LH,Zhu CZ,et al. A simple and sensitive fluorescent sensing platform for Hg(2+) ions assay based on G-quenching[J]. talanta,2011,85(1):713-717. |
| APA | Hu P,Jin LH,Zhu CZ,&Dong SJ.(2011).A simple and sensitive fluorescent sensing platform for Hg(2+) ions assay based on G-quenching.talanta,85(1),713-717. |
| MLA | Hu P,et al."A simple and sensitive fluorescent sensing platform for Hg(2+) ions assay based on G-quenching".talanta 85.1(2011):713-717. |
入库方式： OAI收割
来源：长春应用化学研究所
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