Synthesis of OH-Group-Containing, Biodegradable Polyurethane and Protein Fixation on Its Surface
文献类型：期刊论文
| 作者 | Yang LX ; Wei JZ ; Yan LS ; Huang YB ; Jing XB |
| 刊名 | biomacromolecules
 |
| 出版日期 | 2011 |
| 卷号 | 12期号:6页码:2032-2038 |
| 关键词 | CLICK CHEMISTRY DRUG-DELIVERY POLYMERS FIBERS IMMOBILIZATION ELASTOMERS SCAFFOLDS BEHAVIOR |
| ISSN号 | 1525-7797 |
| 通讯作者 | jing xb |
| 中文摘要 | a series of biodegradable polyurethanes containing free side hydroxyl, groups (puoh) were synthesized successfully in two steps: (1) pla diol as soft segment, hexamethylene diisocyanate (hdi) as hard segment, and benzalpentaerythritol (bpo) as a chain extender were used to synthesize pus with protected oh groups; (2) cf(3)cooh was used as a deprotection agent to remove the benzal groups on pu to prepare puoh the properties of pu and puoh were characterized by fourier transform infrared spectroscopy (ft-ir), nuclear magnetic, resonance (nmr), differential scanning calorimetry (dsc), water contact angle measurement, and gel permeation chromatography (gpc). the benzal groups were removed completely in 15 min without detrimental effect on pu main chain to obtain puohs 4 azidobenzoic acid was conjugated to puoh through its esterification with the free oh groups on puoh. the results of immunofluorescence assay showed that the phenyl azide groups formed were capable of binding mouse igg under uv (254 min) irradiation in 3 min; the bound mouse igg retained it own biological activity and could further bind the fitc-labeled anti(mouse igg). therefore, this material has a potential in immunofluorescence assay and related fields. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000291499900010 |
| 公开日期 | 2012-06-11 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/44600]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yang LX,Wei JZ,Yan LS,et al. Synthesis of OH-Group-Containing, Biodegradable Polyurethane and Protein Fixation on Its Surface[J]. biomacromolecules,2011,12(6):2032-2038. |
| APA | Yang LX,Wei JZ,Yan LS,Huang YB,&Jing XB.(2011).Synthesis of OH-Group-Containing, Biodegradable Polyurethane and Protein Fixation on Its Surface.biomacromolecules,12(6),2032-2038. |
| MLA | Yang LX,et al."Synthesis of OH-Group-Containing, Biodegradable Polyurethane and Protein Fixation on Its Surface".biomacromolecules 12.6(2011):2032-2038. |
入库方式： OAI收割
来源：长春应用化学研究所
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