Single-Particle Tracking of Hepatitis B Virus-like Vesicle Entry into Cells
文献类型：期刊论文
| 作者 | Hao X ; Shang X ; Wu JZ ; Shan YP ; Cai MJ ; Jiang JG ; Huang Z ; Tang ZY ; Wang HD |
| 刊名 | small
 |
| 出版日期 | 2011 |
| 卷号 | 7期号:9页码:1212-1218 |
| ISSN号 | 1613-6810 |
| 关键词 | RECEPTOR-MEDIATED ENDOCYTOSIS INDIVIDUAL INFLUENZA-VIRUSES EPITHELIAL-CELLS MEMBRANE DOMAINS POLIOVIRUS ENTRY VIRAL ENTRY LIVE CELLS CLATHRIN INFECTION TRANSPORT |
| 通讯作者 | huang z |
| 中文摘要 | hbsag, the surface antigen of the hepatitis b virus (hbv), is used as a model to study the mechanisms and dynamics of a single-enveloped virus infecting living cells by imaging and tracking at the single-particle level. by monitoring the fluorescent indicator of hbsag particles, it is found that hbsag enters cells via a caveolin-mediated endocytic pathway. tracking of individual hbsag particles in living cells reveals the anomalously actin-dependent but not microtubule-dependent motility of the internalized hbsag particle. the motility of hbsag particles in living cells is also analyzed quantitatively. these results may settle the long-lasting debate of whether hbv directly breaks the plasma membrane barrier or relies on endocytosis to deliver its genome into the cell, and how the virus moves in the cell. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000289998400012 |
| 公开日期 | 2012-06-11 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/44644]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Hao X,Shang X,Wu JZ,et al. Single-Particle Tracking of Hepatitis B Virus-like Vesicle Entry into Cells[J]. small,2011,7(9):1212-1218. |
| APA | Hao X.,Shang X.,Wu JZ.,Shan YP.,Cai MJ.,...&Wang HD.(2011).Single-Particle Tracking of Hepatitis B Virus-like Vesicle Entry into Cells.small,7(9),1212-1218. |
| MLA | Hao X,et al."Single-Particle Tracking of Hepatitis B Virus-like Vesicle Entry into Cells".small 7.9(2011):1212-1218. |
入库方式： OAI收割
来源：长春应用化学研究所
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