中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Electrostatic-Assembly-Driven Formation of Supramolecular Rhombus Microparticles and Their Application for Fluorescent Nucleic Acid Detection

文献类型:期刊论文

作者Li HL ; Zhai JF ; Sun XP
刊名plos one
出版日期2011
卷号6期号:4页码:1-6
关键词SENSING PLATFORM CARBON NANOTUBES DNA ANALYSIS NANOPARTICLES GRAPHENE PROBES OLIGONUCLEOTIDES BIOMOLECULES
ISSN号1932-6203
通讯作者li hl
中文摘要in this paper, we report on the large-scale formation of supramolecular rhombus microparticles (srms) driven by electrostatic assembly, carried out by direct mixing of an aqueous haucl(4) solution and an ethanol solution of 4,4`-bipyridine at room temperature. we further demonstrate their use as an effective fluorescent sensing platform for nucleic acid detection with a high selectivity down to single-base mismatch. the general concept used in this approach is based on adsorption of the fluorescently labeled single-stranded dna (ssdna) probe by srm, which is accompanied by substantial fluorescence quenching. in the following assay, specific hybridization with its target to form double-stranded dna (dsdna) results in desorption of ssdna from srm surface and subsequent fluorescence recovery.
收录类别SCI收录期刊论文
语种英语
WOS记录号WOS:000289671100040
公开日期2012-06-11
源URL[http://ir.ciac.jl.cn/handle/322003/44691]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式
GB/T 7714
Li HL,Zhai JF,Sun XP. Electrostatic-Assembly-Driven Formation of Supramolecular Rhombus Microparticles and Their Application for Fluorescent Nucleic Acid Detection[J]. plos one,2011,6(4):1-6.
APA Li HL,Zhai JF,&Sun XP.(2011).Electrostatic-Assembly-Driven Formation of Supramolecular Rhombus Microparticles and Their Application for Fluorescent Nucleic Acid Detection.plos one,6(4),1-6.
MLA Li HL,et al."Electrostatic-Assembly-Driven Formation of Supramolecular Rhombus Microparticles and Their Application for Fluorescent Nucleic Acid Detection".plos one 6.4(2011):1-6.

入库方式: OAI收割

来源:长春应用化学研究所

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