Ag@Poly(m-phenylenediamine) Core-Shell Nanoparticles for Highly Selective, Multiplex Nucleic Acid Detection
文献类型：期刊论文
| 作者 | Zhang YW ; Wang L ; Tian JQ ; Li HL ; Luo YL ; Sun XP |
| 刊名 | langmuir
 |
| 出版日期 | 2011 |
| 卷号 | 27期号:6页码:2170-2175 |
| 关键词 | QUENCHED FLUORESCENT OLIGONUCLEOTIDES SILVER NANOPARTICLES HYDROGEN-PEROXIDE POLY(O-PHENYLENEDIAMINE) FILM GOLD NANOPARTICLES AG NANOPARTICLES DNA ANALYSIS PHENYLENEDIAMINE MICROPARTICLES PARTICLES |
| ISSN号 | 0743-7463 |
| 通讯作者 | sun xp |
| 中文摘要 | in this letter, we report on the one-step synthesis of ag@poly(m-phenylenediamine) core-shell nanoparticles (apcsnps), carried out by direct mixing of aqueous silver nitrate and m-phenylenediamine solutions at room temperature. we further demonstrate the use of apcsnp as a novel fluorescent sensing platform for nucleic acid detection. in this regard, the detection of dna is accomplished in two steps. first, apcsnp absorbs and quenches the fluorescence of dye-labeled single-stranded dna (ssdna) as a probe. second, hybridizing of the probe with its target produces a double stranded dna (dsdna) that detaches from apcsnp, resulting in the recovery of dye fluorescence. it suggests that this sensing system has a high selectivity down to single-base mismatch, and the results exhibit good reproducibility. furthermore, we also demonstrate its application for the multiplex detection of nucleic acid sequences. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000288039500022 |
| 公开日期 | 2012-06-11 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/44765]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zhang YW,Wang L,Tian JQ,et al. Ag@Poly(m-phenylenediamine) Core-Shell Nanoparticles for Highly Selective, Multiplex Nucleic Acid Detection[J]. langmuir,2011,27(6):2170-2175. |
| APA | Zhang YW,Wang L,Tian JQ,Li HL,Luo YL,&Sun XP.(2011).Ag@Poly(m-phenylenediamine) Core-Shell Nanoparticles for Highly Selective, Multiplex Nucleic Acid Detection.langmuir,27(6),2170-2175. |
| MLA | Zhang YW,et al."Ag@Poly(m-phenylenediamine) Core-Shell Nanoparticles for Highly Selective, Multiplex Nucleic Acid Detection".langmuir 27.6(2011):2170-2175. |
入库方式： OAI收割
来源：长春应用化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。