Metal-mediated fabrication of new functional G-quartet-based supramolecular nanostructure and potential application as controlled drug release system
文献类型：期刊论文
| 作者 | Hu, D ; Ren, JS ; Qu, XG |
| 刊名 | chemical science
 |
| 出版日期 | 2011 |
| 卷号 | 2期号:7页码:1356-1361 |
| 关键词 | G-QUADRUPLEX STRUCTURES GUANOSINE 5'-MONOPHOSPHATE ALKALI-METAL CATION-BINDING SR2+ ACID DNA D(G(4)T(4)G(4)) INTERCONVERSION AMPLIFICATION |
| ISSN号 | 2041-6520 |
| 通讯作者 | ren js |
| 中文摘要 | the creation and expansion of addressable supramolecular architectures in a facile and economic way with further functions still remain a big challenge in the field of self-assembly. herein, we demonstrated a novel strategy to construct a metal-mediated g-quartet-based supramolecular nanostructure with controllable functions. by using 5'-gmp as basic building blocks in dilute solution, the sr(2+) promoted assemblies are simple and intuitive, yet cost-effective. the resulting structures can be regarded as completely homogeneous from the structural point of view and the nanowires are much longer than those previously reported. the nanowires can be controlled by chemical input signals, namely, divalent metal ions and a chelating agent. furthermore, the encapsulating feature of this system towards g-quadruplex-specific ligands might be of particular biological significance, in the framework of nucleic telomerase. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000291610600021 |
| 公开日期 | 2012-06-11 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/44977]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Hu, D,Ren, JS,Qu, XG. Metal-mediated fabrication of new functional G-quartet-based supramolecular nanostructure and potential application as controlled drug release system[J]. chemical science,2011,2(7):1356-1361. |
| APA | Hu, D,Ren, JS,&Qu, XG.(2011).Metal-mediated fabrication of new functional G-quartet-based supramolecular nanostructure and potential application as controlled drug release system.chemical science,2(7),1356-1361. |
| MLA | Hu, D,et al."Metal-mediated fabrication of new functional G-quartet-based supramolecular nanostructure and potential application as controlled drug release system".chemical science 2.7(2011):1356-1361. |
入库方式： OAI收割
来源：长春应用化学研究所
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