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Potentiometric sensor for sensitive and selective detection of heparin
文献类型：期刊论文
| 作者 | Chen, Yan1,2; Liang, Rong Ning1; Qin, Wei1
|
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2012-02-01 |
| 卷号 | 23期号:2页码:233-236 |
| 关键词 | Potentiometry Sensing element Heparin Protamine Polyion sensor |
| ISSN号 | 1001-8417 |
| 产权排序 | [Chen, Yan; Liang, Rong Ning; Qin, Wei] Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Chen, Yan] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 通讯作者 | Qin, W (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. wqin@yic.ac.cn |
| 中文摘要 | A polymeric membrane ion-selective electrode for determination of heparin is described in this paper. Protamine is incorporated into the organic membrane phase and functions as sensing element for selective recognition of heparin. The proposed membrane electrode exhibits high selectivity for heparin over lipophilic anions such as thiocyanide and salicylate. The potentiometric response to the concentration of heparin is linear in the range of 0.01-0.4 U/mL and a lower detection limit of 0.005 U/mL can be achieved. |
| 英文摘要 | A polymeric membrane ion-selective electrode for determination of heparin is described in this paper. Protamine is incorporated into the organic membrane phase and functions as sensing element for selective recognition of heparin. The proposed membrane electrode exhibits high selectivity for heparin over lipophilic anions such as thiocyanide and salicylate. The potentiometric response to the concentration of heparin is linear in the range of 0.01-0.4 U/mL and a lower detection limit of 0.005 U/mL can be achieved. (C) 2011 Wei Qin. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. |
| 学科主题 | Chemistry |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | MEMBRANE-ELECTRODE ; BIOANALYTICAL APPLICATIONS ; ELECTROCHEMICAL SENSOR |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China[41176081]; Outstanding Youth Natural Science Foundation of Shandong Province[JQ200814]; Taishan Scholar Program of Shandong Province[TS20081159] |
| 原文出处 | http://www.sciencedirect.com/science/journal/10018417 |
| 语种 | 英语 |
| WOS记录号 | WOS:000299917200028 |
| 公开日期 | 2012-06-13 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/5528]  |
| 专题 | 烟台海岸带研究所_近岸生态与环境实验室 |
| 作者单位 | 1.Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Yan,Liang, Rong Ning,Qin, Wei. Potentiometric sensor for sensitive and selective detection of heparin[J]. CHINESE CHEMICAL LETTERS,2012,23(2):233-236. |
| APA | Chen, Yan,Liang, Rong Ning,&Qin, Wei.(2012).Potentiometric sensor for sensitive and selective detection of heparin.CHINESE CHEMICAL LETTERS,23(2),233-236. |
| MLA | Chen, Yan,et al."Potentiometric sensor for sensitive and selective detection of heparin".CHINESE CHEMICAL LETTERS 23.2(2012):233-236. |
入库方式： OAI收割
来源：烟台海岸带研究所
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