中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Sesquiterpenes and acetogenins from the marine red alga Laurencia okamurai

文献类型:期刊论文

作者Li, Xiao-Dong1; Miao, Feng-Ping1; Li, Ke2; Ji, Nai-Yun1
刊名FITOTERAPIA
出版日期2012-04-01
卷号83期号:3页码:518-522
关键词Laurencia okamurai Sesquiterpene Chamigrene Cuparane Acetogenin
ISSN号0367-326X
产权排序[Li, Xiao-Dong; Miao, Feng-Ping; Ji, Nai-Yun] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Li, Ke] Michigan State Univ, E Lansing, MI 48824 USA
通讯作者Ji, NY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. nyji@yic.ac.cn
中文摘要Three new halogenated sesquiterpenes, 10-bromo-7 alpha,8 alpha-expoxychamigr-1-en-3-ol (1), 10-bromo-beta-chamigren-8-ol (2), and 10-bromo-3-chlorocupar-5-en-2-ol (3), one new C-12-acetogenin, desepilaurallene (7), one new naturally occurring sesquiterpene, 7-hydroxylaurene acetate (4), two known sesquiterpenes, allolaurinterol acetate (5) and laurene (6), and one known C-15-acetogenin, epilaurallene (8), were isolated from the marine red alga Laurencia okamurai collected from the coast of Rongcheng, China. The structures of these compounds were unambiguously established by 1D, 2D NMR and mass spectroscopic techniques. The bioassay results showed that 4,5 exhibited potent antibacterial activity, and 1, 4, 5 were toxic to brine shrimp.
英文摘要Three new halogenated sesquiterpenes, 10-bromo-7 alpha,8 alpha-expoxychamigr-1-en-3-ol (1), 10-bromo-beta-chamigren-8-ol (2), and 10-bromo-3-chlorocupar-5-en-2-ol (3), one new C-12-acetogenin, desepilaurallene (7), one new naturally occurring sesquiterpene, 7-hydroxylaurene acetate (4), two known sesquiterpenes, allolaurinterol acetate (5) and laurene (6), and one known C-15-acetogenin, epilaurallene (8), were isolated from the marine red alga Laurencia okamurai collected from the coast of Rongcheng, China. The structures of these compounds were unambiguously established by 1D, 2D NMR and mass spectroscopic techniques. The bioassay results showed that 4,5 exhibited potent antibacterial activity, and 1, 4, 5 were toxic to brine shrimp. (C) 2011 Elsevier B.V. All rights reserved.
学科主题Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]SECONDARY METABOLITES ; NIPPONICA YAMADA ; CONSTITUENTS ; DERIVATIVES ; PLANTS
收录类别SCI
资助信息National Natural Science Foundation of China[41106136, 41106137]; Shandong Province Natural Science Foundation[ZR2009BQ021]; Chinese Academy of Sciences for Key Topics in Innovation Engineering[KZCX2-YW-QN209, KZCX2-YW-225]; Foundation of the Chinese Academy of Sciences
语种英语
WOS记录号WOS:000302109400012
公开日期2012-06-13
源URL[http://ir.yic.ac.cn/handle/133337/5578]  
专题烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
海岸带生物资源高效利用研究与发展中心
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
2.Michigan State Univ, E Lansing, MI 48824 USA
推荐引用方式
GB/T 7714
Li, Xiao-Dong,Miao, Feng-Ping,Li, Ke,et al. Sesquiterpenes and acetogenins from the marine red alga Laurencia okamurai[J]. FITOTERAPIA,2012,83(3):518-522.
APA Li, Xiao-Dong,Miao, Feng-Ping,Li, Ke,&Ji, Nai-Yun.(2012).Sesquiterpenes and acetogenins from the marine red alga Laurencia okamurai.FITOTERAPIA,83(3),518-522.
MLA Li, Xiao-Dong,et al."Sesquiterpenes and acetogenins from the marine red alga Laurencia okamurai".FITOTERAPIA 83.3(2012):518-522.

入库方式: OAI收割

来源:烟台海岸带研究所

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