A novel luminescent mesoporous silica/apatite composite for controlled drug release
文献类型：期刊论文
| 作者 | Yang PP ; Yang P ; Teng X ; Lin J ; Huang L |
| 刊名 | journal of materials chemistry
 |
| 出版日期 | 2011 |
| 卷号 | 21期号:14页码:5505-5510 |
| 关键词 | RESPONSIVE CONTROLLED-RELEASE DELIVERY-SYSTEM SILICA NANOPARTICLES HYDROXYAPATITE SURFACE STRONTIUM PHOSPHORS SHELL CORE FUNCTIONALIZATION |
| ISSN号 | 0959-9428 |
| 通讯作者 | huang l |
| 中文摘要 | a novel bifunctional composite, combining the mesoporous structure of mcm-48 and the self-activated strong blue luminescence of hydroxyapatite (hap), was synthesized and employed for drug delivery and in vitro drug release monitoring in the simulated body fluid (sbf) system. studies have shown that this spherical composite exhibits ordered mesoscale pores, which are suitable to be a carrier for controlled drug release. drug storage/release test indicates that this composite shows high drug loading and well controlled release capability for captopril (caph(2)). particularly, the composite loaded with caph(2) still shows strong blue emission centered at 410 nm under uv excitation, and the luminescence intensity keeps increasing when drug molecules are gradually released from the composite, which shows great potential for controlled drug delivery, in vivo monitoring, and disease diagnosis. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000288659500044 |
| 公开日期 | 2012-06-12 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/45123]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yang PP,Yang P,Teng X,et al. A novel luminescent mesoporous silica/apatite composite for controlled drug release[J]. journal of materials chemistry,2011,21(14):5505-5510. |
| APA | Yang PP,Yang P,Teng X,Lin J,&Huang L.(2011).A novel luminescent mesoporous silica/apatite composite for controlled drug release.journal of materials chemistry,21(14),5505-5510. |
| MLA | Yang PP,et al."A novel luminescent mesoporous silica/apatite composite for controlled drug release".journal of materials chemistry 21.14(2011):5505-5510. |
入库方式： OAI收割
来源：长春应用化学研究所
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