beta-Carboline alkaloids from the leaves of Trigonostemon lii YT Chang
文献类型:期刊论文
作者 | Li, Shi-Fei1,2; Zhang, Yu1![]() ![]() ![]() ![]() |
刊名 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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出版日期 | 2012-03-15 |
卷号 | 22期号:6页码:2296-2299 |
关键词 | Trigonostemon lii beta-Carboline alkaloids Trigonostemines A-F Cytotoxic activity |
ISSN号 | 0960-894X |
通讯作者 | Di, YT (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China, diyt@mail.kib.ac.cn ; hehongping@mail.kib.ac.cn |
英文摘要 | A phytochemical work on the alkaloid constituents from Trigonostemon lii Y.T. Chang was conducted to give six new beta-carboline alkaloids, trigonostemines A-F (1-6) and eight known beta-carboline alkaloids (7-14). Their structures were elucidated by extensive spectroscopic techniques including 2D NMR experiments and mass spectrometry. All of the compounds were evaluated for their cytotoxic activities against the HL-60, SMMC-7721, A-549, MCF-7, and SW480 human cancer cell lines. Trigonostemines A and B (1 and 2) exhibited stronger inhibitory activities than the positive control (cisplatin) in some cell lines. (C) 2012 Elsevier Ltd. All rights reserved. |
学科主题 | Chemistry, Medicinal; Chemistry, Organic |
类目[WOS] | Chemistry, Medicinal ; Chemistry, Organic |
研究领域[WOS] | Pharmacology & Pharmacy ; Chemistry |
关键词[WOS] | REIDIOIDES ; DAPHNANE ; CHINENSIS ; DITERPENOIDS ; REDIOCIDE ; ROOTS ; PLANT |
收录类别 | SCI |
资助信息 | Ministry of Science and Technology of China[2009CB522300, 2009CB940900]; National Natural Science Fund of China[30801434, 21072199, 31100259]; Natural Science Fund of Yunnan Province[2009CD112]; Foundation of Chinese Academy of Sciences; Yong Academic and Technical Leader Raising Foundation of Yunnan Province[2010CI047, 2009CI072] |
语种 | 英语 |
WOS记录号 | WOS:000301285500034 |
公开日期 | 2012-06-07 |
源URL | [http://ir.kib.ac.cn/handle/151853/10391] ![]() |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Shi-Fei,Zhang, Yu,Li, Yan,et al. beta-Carboline alkaloids from the leaves of Trigonostemon lii YT Chang[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2012,22(6):2296-2299. |
APA | Li, Shi-Fei.,Zhang, Yu.,Li, Yan.,Li, Xin-Rao.,Kong, Ling-Mei.,...&Hao, Xiao-Jiang.(2012).beta-Carboline alkaloids from the leaves of Trigonostemon lii YT Chang.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,22(6),2296-2299. |
MLA | Li, Shi-Fei,et al."beta-Carboline alkaloids from the leaves of Trigonostemon lii YT Chang".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 22.6(2012):2296-2299. |
入库方式: OAI收割
来源:昆明植物研究所
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