Three new diterpenes from Jatropha curcas
文献类型：期刊论文
| 作者 | Jie-Qing Liu; Yuan-Feng Yang; Cui-Fang Wang; Yan Li ; Ming-Hua Qiu
|
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2012-01-28 |
| 卷号 | 68期号:4页码:972-976 |
| 关键词 | Jatropha curcas Euphorbiaceae Diterpenoids Cytotoxicity |
| ISSN号 | 0040-4020 |
| 通讯作者 | Qiu, MH (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Photochem & Plant Resources W China, Lanhei Rd 132, Kunming 650204, Yunnan, Peoples R China, mhchiu@mail.kib.ac.cn |
| 英文摘要 | Jatrophalactone (1) and jatrophalone (2), together with jatrophadiketone (3), a 6/6/6 tricyclic diterpene transformed from rhamnofolane skeleton, have been isolated from the methanolic extract of Jatropha curcas. The structures were established on the basis of extensive spectroscopic methods and further confirmed by X-ray crystallographic analysis. The cytotoxicity against selected cell lines was evaluated. Among them, compound 1 displayed cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines with IC50 values of 8.5, 20.6, 19.7, 20.1, and 19.2 mu M, respectively. The possible biosynthetic pathways for 1 and 3 are proposed. (C) 2011 Elsevier Ltd. All rights reserved. |
| 学科主题 | Chemistry, Organic |
| 类目[WOS] | Chemistry, Organic |
| 研究领域[WOS] | Chemistry |
| 收录类别 | SCI ; IC |
| 资助信息 | National Science & Technology Underpin Program[2007BAD32B01-03]; National Special Program of Basic Research[SB2007FY400]; CAS[KSCX2-YW-G-038, 29KZCXZ-XB2-15-03] |
| 语种 | 英语 |
| WOS记录号 | WOS:000300028800004 |
| 公开日期 | 2012-06-07 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/10405]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Jie-Qing Liu,Yuan-Feng Yang,Cui-Fang Wang,et al. Three new diterpenes from Jatropha curcas[J]. TETRAHEDRON,2012,68(4):972-976. |
| APA | Jie-Qing Liu,Yuan-Feng Yang,Cui-Fang Wang,Yan Li,&Ming-Hua Qiu.(2012).Three new diterpenes from Jatropha curcas.TETRAHEDRON,68(4),972-976. |
| MLA | Jie-Qing Liu,et al."Three new diterpenes from Jatropha curcas".TETRAHEDRON 68.4(2012):972-976. |
入库方式： OAI收割
来源：昆明植物研究所
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