New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora
文献类型：期刊论文
| 作者 | Wang, Wei-Guang1,2; Du, Xue1; Li, Xiao-Nian1; Wu, Hai-Yan1; Liu, Xu1; Shang, Shan-Zhai1,2; Zhan, Rui1,2; Liang, Cheng-Gin1,2; Kong, Ling-Mei1,2; Li, Yan1
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| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2012-01-06 |
| 卷号 | 14期号:1页码:302-305 |
| ISSN号 | 1523-7060 |
| 关键词 | Synthesis Caudatin derivatives Anti-HBV activity Structure-activity relationships IN-VITRO HBV INHIBITORS INFECTION ALISOL |
| 通讯作者 | Pu, JX (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China, pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn |
| 英文摘要 | Neolaxiflorin A (1), an unprecedented ent-kaurane diterpenoid with a bicyclo[3.1.0]hexane unit, and its seco-derivative, neolaxiflorin B (2), along with two known compounds 3 and 4 were isolated from the leaves of Isodon erlocalyx var. laxiflora. The absolute configuration of 1 was determined by spectral methods and single crystal X-ray diffraction analysis. Compound 4 and the synthesized compound 5 exhibited significant cytotoxicity. |
| 学科主题 | Chemistry ; Organic |
| 类目[WOS] | Chemistry, Organic |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | MAOECRYSTAL-V ; KAPPA-B ; CARBOCYCLIC NUCLEOSIDES ; OXIDATIVE CYCLIZATION ; RECEPTOR ; ANALOGS ; BINDING ; ENYNES ; CELLS ; CYCLOISOMERIZATION |
| 资助信息 | NSFC-Joint Foundation of Yunnan Province[U0832602]; National Natural Science Foundation of China[81172939]; Major State Basic Research Development Program of China[2009CB522300]; the reservation-talent project of Yunnan Province[2011CI043]; Science and Technology Program of Yunan Province[2008IF010, 2008CD162]; Major Direction Projection Foundation of CAS[2010KIBA05] |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000298828500078 |
| 公开日期 | 2012-06-07 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/10437]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Wei-Guang,Du, Xue,Li, Xiao-Nian,et al. New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora[J]. ORGANIC LETTERS,2012,14(1):302-305. |
| APA | Wang, Wei-Guang.,Du, Xue.,Li, Xiao-Nian.,Wu, Hai-Yan.,Liu, Xu.,...&Sun, Han-Dong.(2012).New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora.ORGANIC LETTERS,14(1),302-305. |
| MLA | Wang, Wei-Guang,et al."New Bicyclo[3.1.0]hexane Unit ent-Kaurane Diterpene and Its seco-Derivative from Isodon eriocalyx var. laxiflora".ORGANIC LETTERS 14.1(2012):302-305. |
入库方式： OAI收割
来源：昆明植物研究所
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