蛋白质自由基损伤的保护和修复
文献类型：期刊论文
| 作者 | 朱红平,张兆霞,赵红卫,葛敏,王文锋,姚思德 |
| 刊名 | 辐射研究与辐射工艺学报
 |
| 出版日期 | 2005-04-30 |
| 期号 | 02 |
| 关键词 | 活性氧 抗氧化剂 蛋白 |
| 通讯作者 | 朱红平 |
| 中文摘要 | Reactive oxygen species (ROS) induce a lot of disease when the balance breaks between ROS and the enzymic and non-znzymic systems in human body to effectively scavenge ROS and prevent them from damaging the body. Proteins, which account for about 20% dry weight of a human cell, may be major target of attacks by ROS. It has been found that hydroxycinnamic acid, flavonoids and some other natural anti-oxidants can scavenge ROS inside body organs and tissues, and repair effectively oxidization damages to proteins. In recent years, stud- ies have been focused on mechanisms of the ROS caused damages to proteins, and on protecting proteins against ROS. In the meantime, explorations have been made on analyzing stable products of proteins involved in oxidation by ROS and on relationships between scavenging effects of natural anti-oxidants and their molecular structures. However, there are problems remaining before us for answers by still more investigations, such as what is the ROS attacking position on a protein macromolecule and how is the molecular modification of the ROS-attacked protein. |
| 收录类别 | CNKI |
| 公开日期 | 2012-07-04 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/9277]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2004-2010年 |
| 推荐引用方式 GB/T 7714 | 朱红平,张兆霞,赵红卫,葛敏,王文锋,姚思德. 蛋白质自由基损伤的保护和修复[J]. 辐射研究与辐射工艺学报,2005(02). |
| APA | 朱红平,张兆霞,赵红卫,葛敏,王文锋,姚思德.(2005).蛋白质自由基损伤的保护和修复.辐射研究与辐射工艺学报(02). |
| MLA | 朱红平,张兆霞,赵红卫,葛敏,王文锋,姚思德."蛋白质自由基损伤的保护和修复".辐射研究与辐射工艺学报 .02(2005). |
入库方式： OAI收割
来源：上海应用物理研究所
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