Detecting small lung tumors in mouse models by refractive-index microradiology
文献类型：期刊论文
| 作者 | Chien, Chia-Chi ; Zhang, Guilin（张桂林） ; Hwu, Y. ; Liu, Ping（刘平） ; Yue, Weisheng（岳伟胜） ; Sun, Jianqi ; Li, Yan（李燕） ; Xue, Hongjie ; Xu, Lisa X. ; Wang, Chang Hai ; Chen, Nanyow ; Lu, Chien Hung ; Lee, Ting-Kuo ; Yang, Yuh-Cheng ; Lu, Yen-Ta ; Ching, Yu-Tai ; Shih, T. F. ; Yang, P. C. ; Je, J. H. ; Margaritondo, G. |
| 刊名 | ANALYTICAL AND BIOANALYTICAL CHEMISTRY
 |
| 出版日期 | 2011 |
| 卷号 | 401期号:3页码:827 |
| ISSN号 | 1618-2642 |
| 英文摘要 | Refractive-index (phase-contrast) radiology was able to detect lung tumors less than 1 mm in live mice. Significant micromorphology differences were observed in the microradiographs between normal, inflamed, and lung cancer tissues. This was made possible by the high phase contrast and by the fast image taking that reduces the motion blur. The detection of cancer and inflammation areas by phase contrast microradiology and microtomography was validated by bioluminescence and histopathological analysis. The smallest tumor detected is less than 1 mm(3) with accuracy better than 1 x 10(-3) mm(3). This level of performance is currently suitable for animal studies, while further developments are required for clinical application. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000292970200007 |
| 公开日期 | 2012-07-04 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/9483]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Chien, Chia-Chi,Zhang, Guilin,Hwu, Y.,et al. Detecting small lung tumors in mouse models by refractive-index microradiology[J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY,2011,401(3):827. |
| APA | Chien, Chia-Chi.,Zhang, Guilin.,Hwu, Y..,Liu, Ping.,Yue, Weisheng.,...&Margaritondo, G..(2011).Detecting small lung tumors in mouse models by refractive-index microradiology.ANALYTICAL AND BIOANALYTICAL CHEMISTRY,401(3),827. |
| MLA | Chien, Chia-Chi,et al."Detecting small lung tumors in mouse models by refractive-index microradiology".ANALYTICAL AND BIOANALYTICAL CHEMISTRY 401.3(2011):827. |
入库方式： OAI收割
来源：上海应用物理研究所
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