Nondestructive Imaging of Elements Distribution in Biomedical Samples by X-Ray Fluorescence Computed Tomography
文献类型:期刊论文
作者 | Yang Qun(杨群) ; Deng Biao(邓彪) ; Lu Wei-wei ; Du Guo-hao(杜国浩) ; Yan Fu-hua ; Xiao Ti-qiao(肖体乔) ; Xu Hong-jie(徐洪杰) |
刊名 | SPECTROSCOPY AND SPECTRAL ANALYSIS
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出版日期 | 2011 |
卷号 | 31期号:10页码:2753 |
ISSN号 | 1000-0593 |
英文摘要 | X-ray fluorescence computed tomography is a stimulated emission tomography that allows nondestructive reconstruction of the elements distribution in the sample, which is important for biomedical investigations. Owing to the high flux density and easy energy tunability of highly collimated synchrotron X-rays, it is possible to apply X-ray fluorescence CT to biomedical samples. Reported in the present paper, an X-ray fluorescence CT system was established at Shanghai Synchrotron Radiation Facility for the investigations of trace elements distribution inside biomedical samples. By optimizing the experiment setup, the spatial resolution was improved and the data acquisition process was obviously speeded up. The maximum-likelihood expectation-maximization algorithm was introduced for the image reconstruction, which remarkably improved the imaging accuracy of element distributions. The developed system was verified by the test sample and medical sample respectively. The results showed that the distribution of interested elements could be imaged correctly, and the spatial resolution of 150 m was achieved. In conclusion, the developed system could be applied to the research on large-size biomedical samples, concerning imaging accuracy, spatial resolution and data collection time. |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000295556300036 |
公开日期 | 2012-07-04 |
源URL | [http://ir.sinap.ac.cn/handle/331007/9557] ![]() |
专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
推荐引用方式 GB/T 7714 | Yang Qun,Deng Biao,Lu Wei-wei,et al. Nondestructive Imaging of Elements Distribution in Biomedical Samples by X-Ray Fluorescence Computed Tomography[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS,2011,31(10):2753. |
APA | Yang Qun.,Deng Biao.,Lu Wei-wei.,Du Guo-hao.,Yan Fu-hua.,...&Xu Hong-jie.(2011).Nondestructive Imaging of Elements Distribution in Biomedical Samples by X-Ray Fluorescence Computed Tomography.SPECTROSCOPY AND SPECTRAL ANALYSIS,31(10),2753. |
MLA | Yang Qun,et al."Nondestructive Imaging of Elements Distribution in Biomedical Samples by X-Ray Fluorescence Computed Tomography".SPECTROSCOPY AND SPECTRAL ANALYSIS 31.10(2011):2753. |
入库方式: OAI收割
来源:上海应用物理研究所
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