Photosensitized xanthone-based oxidation of guanine and its repair: A laser flash photolysis study
文献类型：期刊论文
| 作者 | Tang, Ruizhi（唐睿智） ; Zhang, Peng（张鹏） ; Li, Haixia（李海霞） ; Liu, Yancheng ; Wang, Wenfeng（王文峰） |
| 刊名 | JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
 |
| 出版日期 | 2011 |
| 卷号 | 105期号:2页码:157 |
| ISSN号 | 1011-1344 |
| 英文摘要 | The photosensitized oxidation of guanine (G) by the triplet state of xanthone (XT) and the repair for photo-damaged G(-H)(center dot) by ferulic acid (FCA) were investigated using the laser flash photolysis technique. The rate constants of the reaction of triplet state of XT with G and with FCA were determined as 4.5 x 10(9) and 8.0 x 10(9) L mol(-1)s(-1), respectively. Laser exposure was performed on the N(2)-saturated acetonitrile/water (v/v, 1:1) solution containing G, XT and FCA. The transient absorption spectra indicated that the triplet state of XT first reacted with G predominantly to form the oxidized radical G(-H)(center dot). The radical G(-H)(center dot) was rapidly repaired by FCA, and the rate constant for the repair reaction was determined as 1.1 x 10(9) L mol(-1) s(-1). These results demonstrated that non-enzymatic repair is a feasible method for repairing photosensitized DNA bases oxidation. (C) 2011 Elsevier B.V. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000296678600006 |
| 公开日期 | 2012-07-04 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/9564]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Tang, Ruizhi,Zhang, Peng,Li, Haixia,et al. Photosensitized xanthone-based oxidation of guanine and its repair: A laser flash photolysis study[J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,2011,105(2):157. |
| APA | Tang, Ruizhi,Zhang, Peng,Li, Haixia,Liu, Yancheng,&Wang, Wenfeng.(2011).Photosensitized xanthone-based oxidation of guanine and its repair: A laser flash photolysis study.JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,105(2),157. |
| MLA | Tang, Ruizhi,et al."Photosensitized xanthone-based oxidation of guanine and its repair: A laser flash photolysis study".JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY 105.2(2011):157. |
入库方式： OAI收割
来源：上海应用物理研究所
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