Silicon nanowires-based highly-efficient SERS-active platform for ultrasensitive DNA detection
文献类型：期刊论文
| 作者 | He, Yao ; Su, Shao ; Xu, Tingting ; Zhong, Yiling ; Zapien, J. Antonio ; Li, Jiang ; Fan, Chunhai（樊春海） ; Lee, Shuit-Tong |
| 刊名 | NANO TODAY
 |
| 出版日期 | 2011 |
| 卷号 | 6期号:2页码:122 |
| ISSN号 | 1748-0132 |
| 英文摘要 | A nanostructured complex, silicon nanowires (SiNWs) coated with in situ grown AgNPs (SiNWs@AgNPs), is developed as a well-defined surface-enhanced Raman Scattering (SERS)-active platform for ultrasensitive DNA detection. Such SiNWs@AgNPs nanostructure possesses an extremely high SERS enhancement factor of similar to 10(10). We design a DNA sensor based on the nanostructure via immobilization of capture probe DNA at the surface of AgNPs, and a sandwich strategy for the detection of target DNA that brings a reporter probe labeled with a dye to the proximity of the surface, leading to high SERS signals. This silicon nanostructure-based biosensor platform can detect a remarkably low DNA concentration at similar to 1 fM, which is comparable to the lowest DNA concentration ever detected via SERS. We expect this highly sensitive and robust SiNWs-based SERS platform may serve as a practical and powerful tool for biomolecular sensing and biomedical analysis. (C) 2011 Elsevier Ltd. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000290507200006 |
| 公开日期 | 2012-07-04 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/9587]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | He, Yao,Su, Shao,Xu, Tingting,et al. Silicon nanowires-based highly-efficient SERS-active platform for ultrasensitive DNA detection[J]. NANO TODAY,2011,6(2):122. |
| APA | He, Yao.,Su, Shao.,Xu, Tingting.,Zhong, Yiling.,Zapien, J. Antonio.,...&Lee, Shuit-Tong.(2011).Silicon nanowires-based highly-efficient SERS-active platform for ultrasensitive DNA detection.NANO TODAY,6(2),122. |
| MLA | He, Yao,et al."Silicon nanowires-based highly-efficient SERS-active platform for ultrasensitive DNA detection".NANO TODAY 6.2(2011):122. |
入库方式： OAI收割
来源：上海应用物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。