Melophlins C-O, thirteen novel tetramic acids from the marine sponge Melophlus sarassinorum
文献类型：期刊论文
| 作者 | Wang, CY; Wang, BG; Wiryowidagdo, S; Wray, V; van Soest, R; Steube, KG; Guan, HS; Proksch, P; Ebel, R |
| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2003 |
| 卷号 | 66期号:1页码:51-56 |
| ISSN号 | 0163-3864 |
| 通讯作者 | ebel@uni-duesseldorf.de |
| 英文摘要 | Thirteen new metabolites, melophlins C-O (1-13), were identified from the marine sponge Melophlus sarassinorum. Compounds 1-13 represent tetramic acid derivatives that differ with regard to the nature of their alkyl side chains. The structures of the new compounds were elucidated on the basis of comprehensive spectral analysis (H-1, C-13, H-1-H-1 COSY, HMQC, and HMBC NMR, as well as low- and high-resolution ESIMS and EIMS). The absolute configurations of 1, 8, 10, 11, 12, and 13 were determined by ESI LC/MS analysis of chiral derivatives obtained upon oxidation and hydrolysis of the respective parent compounds. Melophlin C (1) displayed pronounced antibacterial activity against Bacillus subtilis and Staphylococcus aureus, together with antifungal activity against Candida albicans. |
| 学科主题 | Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | CONSTITUENT AMINO-ACIDS ; ABSOLUTE-CONFIGURATION ; SILIQUARIASPONGIA-JAPONICA ; MARFEYS METHOD ; METABOLITES ; GLYCOSIDES ; PEPTIDE ; LC/MS ; INHIBITORS ; EQUISETIN |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000180623400012 |
| 公开日期 | 2012-07-04 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/13465]  |
| 专题 | 昆明植物研究所_离退休 |
| 作者单位 | 1.Univ Dusseldorf, Inst Pharmazeut Biol, D-40225 Dusseldorf, Germany 2.Univ Indonesia, Ctr Marine Studies, Depok 16424, Indonesia 3.Gesell Biotechnol Forsch mbH, D-38124 Braunschweig, Germany 4.Univ Amsterdam, Zool Museum, NL-1092 AD Amsterdam, Netherlands 5.Deutsch Sammlung Mikroorganismen & Zellkulturen G, D-38124 Braunschweig, Germany 6.Ocean Univ Qingdao, Marine Drug & Food Inst, Qingdao 266003, Peoples R China 7.Chinese Acad Sci, Lab Phytochem, Kunming Inst Bot, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, CY,Wang, BG,Wiryowidagdo, S,et al. Melophlins C-O, thirteen novel tetramic acids from the marine sponge Melophlus sarassinorum[J]. JOURNAL OF NATURAL PRODUCTS,2003,66(1):51-56. |
| APA | Wang, CY.,Wang, BG.,Wiryowidagdo, S.,Wray, V.,van Soest, R.,...&Ebel, R.(2003).Melophlins C-O, thirteen novel tetramic acids from the marine sponge Melophlus sarassinorum.JOURNAL OF NATURAL PRODUCTS,66(1),51-56. |
| MLA | Wang, CY,et al."Melophlins C-O, thirteen novel tetramic acids from the marine sponge Melophlus sarassinorum".JOURNAL OF NATURAL PRODUCTS 66.1(2003):51-56. |
入库方式： OAI收割
来源：昆明植物研究所
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