Abietane diterpenoids synthesized by suspension-cultured cells of Cephalotaxus fortunei
文献类型：期刊论文
| 作者 | Xu, Xiao-Hui1,2; Zhang, Wei1,3,4; Cao, Xu-Peng1; Xue, Song1 |
| 刊名 | phytochemistry letters
 |
| 出版日期 | 2011-03-15 |
| 卷号 | 4期号:1页码:52-55 |
| 关键词 | Abietane diterpenoids Elicitation In situ product removal Cephalotaxus fortunei Cell suspension culture |
| ISSN号 | 待补充 |
| 产权排序 | 1,1 |
| 通讯作者 | 张卫 |
| 中文摘要 | abietane diterpenoids synthesized by suspension-cultured cells of cephalotaxus fortunei |
| 英文摘要 | cell suspension cultures of cephalotaxus fortunei were manipulated to produce secondary metabolites of pharmaceutical interest. seven abietane diterpenoids (six known and one new) were produced by the suspension-cultured c. fortunei cells by complementing an elicitation strategy with an in situ product removal strategy. based on the results of spectrometric analysis, the structure of the new compound was determined to be 20(10 -> 5)-abeo-4,5-seco-5(10), 6,8,11,13-abietapentaene-3-one (1). the six known compounds were identified as 12-hydroxyabieta-6,8,11,13-tetraene-3-one (2), abieta-8,11,13-triene-3 beta, 12-diol (hinokiol) (3), abietatriene-3 beta-ol (4), 11,12-dihydroxy-8,11,13-abietatriene-3,7-dione (5), 11-hydroxy-12-methoxyabieta-8,11,13-triene-3,7-dione (6), and 3 beta, 11-dihydroxy-12-methoxyabieta-8,11,13- triene-7-one (7). this is the first time that diterpenoids have been isolated and identified from this pharmaceutically important plant. these results suggest that the strategies we applied were effective methods for synthesizing abietane diterpenoids via a suspension culture of c. fortunei cells. (c) 2011 phytochemical society of europe. published by elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 学科主题 | 物理化学 |
| 类目[WOS] | biochemistry & molecular biology ; plant sciences |
| 研究领域[WOS] | biochemistry & molecular biology ; plant sciences |
| 关键词[WOS] | secondary metabolites ; callus ; homoharringtonine ; harringtonine ; yunnanensis |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000287850100010 |
| 公开日期 | 2012-07-09 |
| 源URL | [http://159.226.238.44/handle/321008/115192]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Marine Bioprod Engn Grp, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Flinders Univ S Australia, Flinders Ctr Marine Bioproc & Bioprod, Adelaide, SA 5042, Australia 4.Flinders Univ S Australia, Dept Med Biotechnol, Sch Med, Adelaide, SA 5042, Australia |
| 推荐引用方式 GB/T 7714 | Xu, Xiao-Hui,Zhang, Wei,Cao, Xu-Peng,et al. Abietane diterpenoids synthesized by suspension-cultured cells of Cephalotaxus fortunei[J]. phytochemistry letters,2011,4(1):52-55. |
| APA | Xu, Xiao-Hui,Zhang, Wei,Cao, Xu-Peng,&Xue, Song.(2011).Abietane diterpenoids synthesized by suspension-cultured cells of Cephalotaxus fortunei.phytochemistry letters,4(1),52-55. |
| MLA | Xu, Xiao-Hui,et al."Abietane diterpenoids synthesized by suspension-cultured cells of Cephalotaxus fortunei".phytochemistry letters 4.1(2011):52-55. |
入库方式： OAI收割
来源：大连化学物理研究所
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