Synthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactors
文献类型：期刊论文
| 作者 | Hou, Shuhua1,2; Liu, Wujun1; Ji, Debin1,2; Wang, Qian1; Zhao, Zongbao Kent1,3 |
| 刊名 | tetrahedron letters
 |
| 出版日期 | 2011-11-02 |
| 卷号 | 52期号:44页码:5855-5857 |
| 关键词 | NAD analogs Malic enzyme Alcohol dehydrogenase Promiscuity |
| ISSN号 | 待补充 |
| 产权排序 | 1,1 |
| 通讯作者 | 赵宗保 |
| 中文摘要 | synthesis of 1,2,3-triazole moiety-containing nad analogs and their potential as redox cofactors |
| 英文摘要 | thirteen 1,2,3-triazole moiety-containing nad analogs were synthesized and evaluated as redox cofactors. noticeable enzymatic activities were observed when these analogs were employed as cofactors for malic enzyme or alcohol dehydrogenase. our results indicated that the natural nad-dependent oxidoreductases possessed flexible nad binding pockets. (c) 2011 elsevier ltd. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 学科主题 | 物理化学 |
| 类目[WOS] | chemistry, organic |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | chemical-synthesis ; dehydrogenase ; coenzymes ; evolution ; ribose |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000296168300033 |
| 公开日期 | 2012-07-09 |
| 源URL | [http://159.226.238.44/handle/321008/115573]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.CAS, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China 3.Dalian Natl Lab Clean Energy, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hou, Shuhua,Liu, Wujun,Ji, Debin,et al. Synthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactors[J]. tetrahedron letters,2011,52(44):5855-5857. |
| APA | Hou, Shuhua,Liu, Wujun,Ji, Debin,Wang, Qian,&Zhao, Zongbao Kent.(2011).Synthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactors.tetrahedron letters,52(44),5855-5857. |
| MLA | Hou, Shuhua,et al."Synthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactors".tetrahedron letters 52.44(2011):5855-5857. |
入库方式： OAI收割
来源：大连化学物理研究所
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