Large-scale N-glycoproteome map of rat brain tissue: Simultaneous characterization of insoluble and soluble protein fractions
文献类型：期刊论文
| 作者 | Qiao, Xiaoqiang1,2,3; Tao, Dingyin1; Qu, Yanyan1; Sun, Liangliang1; Gao, Liang1; Zhang, Xiaodan1; Liang, Zhen1; Zhang, Lihua1; Zhang, Yukui1 |
| 刊名 | proteomics
 |
| 出版日期 | 2011-11-01 |
| 卷号 | 11期号:21页码:4274-4278 |
| 关键词 | Glycoproteomics Hydrazide chemistry Insoluble and soluble protein fraction Ionic liquid N-glycoproteome Rat brain |
| ISSN号 | 待补充 |
| 产权排序 | 1,1 |
| 通讯作者 | 张丽华 |
| 中文摘要 | large-scale n-glycoproteome map of rat brain tissue: simultaneous characterization of insoluble and soluble protein fractions |
| 英文摘要 | the large-scale n-glycosylation analysis is critical for biomedical research, since a variety of diseases are found to be associated with glycoproteins. by a combination of glycoprotein analysis in insoluble protein fraction solubilized with 1% v/v 1-butyl-3-methylimidazolium tetrafluoroborate (bmim bf(4)) and those in soluble fraction, a total number of 462 non-redundant n-glycoprotein groups, including 316 transmembrane glycoproteins, were successfully identified. correspondingly, 849 unique n-glycosites were confidently recognized. the data set could provide a support for the further in-depth research of brain n-glycosylation, such as for the discovery of candidate drug targets and biomarkers. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 学科主题 | 物理化学 |
| 类目[WOS] | biochemical research methods ; biochemistry & molecular biology |
| 研究领域[WOS] | biochemistry & molecular biology |
| 关键词[WOS] | titanium-dioxide chromatography ; mass-spectrometry ; membrane proteome ; linked glycoproteins ; selective enrichment ; lc-ms/ms ; in-vivo ; identification ; cancer ; quantification |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000297223200015 |
| 公开日期 | 2012-07-09 |
| 源URL | [http://159.226.238.44/handle/321008/115643]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Natl Chromatog Res & Anal Ctr, Dalian 116023, Peoples R China 2.Hebei Univ, Coll Pharmaceut Sci, Baoding, Peoples R China 3.Hebei Univ, Key Lab Pharmaceut Qual Control Hebei Prov, Baoding, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiao, Xiaoqiang,Tao, Dingyin,Qu, Yanyan,et al. Large-scale N-glycoproteome map of rat brain tissue: Simultaneous characterization of insoluble and soluble protein fractions[J]. proteomics,2011,11(21):4274-4278. |
| APA | Qiao, Xiaoqiang.,Tao, Dingyin.,Qu, Yanyan.,Sun, Liangliang.,Gao, Liang.,...&Zhang, Yukui.(2011).Large-scale N-glycoproteome map of rat brain tissue: Simultaneous characterization of insoluble and soluble protein fractions.proteomics,11(21),4274-4278. |
| MLA | Qiao, Xiaoqiang,et al."Large-scale N-glycoproteome map of rat brain tissue: Simultaneous characterization of insoluble and soluble protein fractions".proteomics 11.21(2011):4274-4278. |
入库方式： OAI收割
来源：大连化学物理研究所
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