中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Molecularly imprinted macroporous monolithic materials for protein recognition

文献类型:期刊论文

作者Deng, Qi Liang1,2; Li, Yan Li1; Zhang, Li Hua2; Zhang, Yu Kui2
刊名chinese chemical letters
出版日期2011-11-01
卷号22期号:11页码:1351-1354
关键词Molecularly imprinted polymers Protein Monolithic column High performance liquid chromatography
ISSN号待补充
产权排序2,1
通讯作者邓启良 ; 张丽华
中文摘要molecularly imprinted macroporous monolithic materials for protein recognition
英文摘要synthetic materials that can specifically recognize proteins will find wide application in many fields. in this report, bovine serum albumin was chosen as the template protein. acrylamide and n,n'-methylenebisacrylamide were employed as the functional and cross-linker monomers, respectively. molecularly imprinted macroporous monolithic materials that can preferentially bind the template protein in an aqueous environment were prepared by combination of molecular imprinting technique and freezing/thawing preparation method. the resulted imprinted macroporous monolithic columns were evaluated by utilizing as stationary phase in high performance liquid chromatography and solid-phase extraction materials. the experimental results indicated that the imprinted macroporous monolithic column exhibited good recognition for template protein, as compared with the control protein (hemoglobin), whereas the non-imprinted polymer (prepared under the same conditions except without addition template protein) had no selective properties. (c) 2011 qi liang deng. published by elsevier b.v. on behalf of chinese chemical society. all rights reserved.
WOS标题词science & technology ; physical sciences
学科主题物理化学
类目[WOS]chemistry, multidisciplinary
研究领域[WOS]chemistry
关键词[WOS]liquid-chromatography ; stationary phases ; polymers ; enantiomers ; separation
收录类别SCI
语种英语
WOS记录号WOS:000296223400023
公开日期2012-07-09
源URL[http://159.226.238.44/handle/321008/115644]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.Tianjin Univ Sci & Technol, Dept Sci, Tianjin 300222, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Deng, Qi Liang,Li, Yan Li,Zhang, Li Hua,et al. Molecularly imprinted macroporous monolithic materials for protein recognition[J]. chinese chemical letters,2011,22(11):1351-1354.
APA Deng, Qi Liang,Li, Yan Li,Zhang, Li Hua,&Zhang, Yu Kui.(2011).Molecularly imprinted macroporous monolithic materials for protein recognition.chinese chemical letters,22(11),1351-1354.
MLA Deng, Qi Liang,et al."Molecularly imprinted macroporous monolithic materials for protein recognition".chinese chemical letters 22.11(2011):1351-1354.

入库方式: OAI收割

来源:大连化学物理研究所

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