Molecularly imprinted macroporous monolithic materials for protein recognition
文献类型:期刊论文
作者 | Deng, Qi Liang1,2; Li, Yan Li1; Zhang, Li Hua2; Zhang, Yu Kui2 |
刊名 | chinese chemical letters
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出版日期 | 2011-11-01 |
卷号 | 22期号:11页码:1351-1354 |
关键词 | Molecularly imprinted polymers Protein Monolithic column High performance liquid chromatography |
ISSN号 | 待补充 |
产权排序 | 2,1 |
通讯作者 | 邓启良 ; 张丽华 |
中文摘要 | molecularly imprinted macroporous monolithic materials for protein recognition |
英文摘要 | synthetic materials that can specifically recognize proteins will find wide application in many fields. in this report, bovine serum albumin was chosen as the template protein. acrylamide and n,n'-methylenebisacrylamide were employed as the functional and cross-linker monomers, respectively. molecularly imprinted macroporous monolithic materials that can preferentially bind the template protein in an aqueous environment were prepared by combination of molecular imprinting technique and freezing/thawing preparation method. the resulted imprinted macroporous monolithic columns were evaluated by utilizing as stationary phase in high performance liquid chromatography and solid-phase extraction materials. the experimental results indicated that the imprinted macroporous monolithic column exhibited good recognition for template protein, as compared with the control protein (hemoglobin), whereas the non-imprinted polymer (prepared under the same conditions except without addition template protein) had no selective properties. (c) 2011 qi liang deng. published by elsevier b.v. on behalf of chinese chemical society. all rights reserved. |
WOS标题词 | science & technology ; physical sciences |
学科主题 | 物理化学 |
类目[WOS] | chemistry, multidisciplinary |
研究领域[WOS] | chemistry |
关键词[WOS] | liquid-chromatography ; stationary phases ; polymers ; enantiomers ; separation |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000296223400023 |
公开日期 | 2012-07-09 |
源URL | [http://159.226.238.44/handle/321008/115644] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | 1.Tianjin Univ Sci & Technol, Dept Sci, Tianjin 300222, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China |
推荐引用方式 GB/T 7714 | Deng, Qi Liang,Li, Yan Li,Zhang, Li Hua,et al. Molecularly imprinted macroporous monolithic materials for protein recognition[J]. chinese chemical letters,2011,22(11):1351-1354. |
APA | Deng, Qi Liang,Li, Yan Li,Zhang, Li Hua,&Zhang, Yu Kui.(2011).Molecularly imprinted macroporous monolithic materials for protein recognition.chinese chemical letters,22(11),1351-1354. |
MLA | Deng, Qi Liang,et al."Molecularly imprinted macroporous monolithic materials for protein recognition".chinese chemical letters 22.11(2011):1351-1354. |
入库方式: OAI收割
来源:大连化学物理研究所
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