Plasma and Liver Lipidomics Response to an Intervention of Rimonabant in ApoE*3Leiden.CETP Transgenic Mice
文献类型：期刊论文
| 作者 | Hu, Chunxiu1,2; Wei, Heng3,6; van den Hoek, Anita M.5; Wang, Mei3,4; van der Heijden, Rob2; Spijksma, Gerwin2; Reijmers, Theo H.2; Bouwman, Jildau6,7; Wopereis, Suzan6; Havekes, Louis M.5 |
| 刊名 | plos one
 |
| 出版日期 | 2011-05-17 |
| 卷号 | 6期号:5页码:e19423 |
| ISSN号 | 待补充 |
| 产权排序 | 1,1 |
| 通讯作者 | 许国旺 ; vandergreefjan |
| 中文摘要 | plasma and liver lipidomics response to an intervention of rimonabant in apoe*3leiden.cetp transgenic mice |
| 英文摘要 | background: lipids are known to play crucial roles in the development of life-style related risk factors such as obesity, dyslipoproteinemia, hypertension and diabetes. the first selective cannabinoid-1 receptor blocker rimonabant, an anorectic anti-obesity drug, was frequently used in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m(2) with associated risk factors such as type ii diabetes and dyslipidaemia in the past. less is known about the impact of this drug on the regulation of lipid metabolism in plasma and liver in the early stage of obesity. |
| WOS标题词 | science & technology |
| 学科主题 | 物理化学 |
| 类目[WOS] | multidisciplinary sciences |
| 研究领域[WOS] | science & technology - other topics |
| 关键词[WOS] | cholesteryl ester transfer ; cardiovascular risk-factors ; increases hdl-cholesterol ; cb1 receptor antagonist ; free fatty-acids ; transfer protein ; aggravates atherosclerosis ; overweight patients ; metabolic syndrome ; hepatic steatosis |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000290657500004 |
| 公开日期 | 2012-07-09 |
| 源URL | [http://159.226.238.44/handle/321008/115681]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian, Peoples R China 2.Leiden Univ, Leiden Amsterdam Ctr Drug Res, Div Analyt Biosci, Leiden, Netherlands 3.Sino Dutch Ctr Prevent & Personalized Med, Zeist, Netherlands 4.SU BioMed, Zeist, Netherlands 5.TNO, Gaubius Lab, Leiden, Netherlands 6.TNO, Dept Earth Environm & Life Sci, NL-3700 AJ Zeist, Netherlands 7.Leiden Univ, Leiden Amsterdam Ctr Drug Res, Netherlands Metab Ctr, Leiden, Netherlands |
| 推荐引用方式 GB/T 7714 | Hu, Chunxiu,Wei, Heng,van den Hoek, Anita M.,et al. Plasma and Liver Lipidomics Response to an Intervention of Rimonabant in ApoE*3Leiden.CETP Transgenic Mice[J]. plos one,2011,6(5):e19423. |
| APA | Hu, Chunxiu.,Wei, Heng.,van den Hoek, Anita M..,Wang, Mei.,van der Heijden, Rob.,...&van der Greef, Jan.(2011).Plasma and Liver Lipidomics Response to an Intervention of Rimonabant in ApoE*3Leiden.CETP Transgenic Mice.plos one,6(5),e19423. |
| MLA | Hu, Chunxiu,et al."Plasma and Liver Lipidomics Response to an Intervention of Rimonabant in ApoE*3Leiden.CETP Transgenic Mice".plos one 6.5(2011):e19423. |
入库方式： OAI收割
来源：大连化学物理研究所
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