Bioactive Compounds from the Aerial Parts of Brachystemma calycinum and Structural Revision of an Octacyclopeptide
文献类型：期刊论文
| 作者 | Zhao, Jun2; Zhou, Li-Li1; Li, Xi3; Xiao, Hong-Bin4; Hou, Fan-Fan1; Cheng, Yong-Xian2 |
| 刊名 | journal of natural products
 |
| 出版日期 | 2011-06-01 |
| 卷号 | 74期号:6页码:1392-1400 |
| ISSN号 | 待补充 |
| 产权排序 | 4,4 |
| 通讯作者 | yong-xiancheng |
| 中文摘要 | bioactive compounds from the aerial parts of brachystemma calycinum and structural revision of an octacyclopeptide |
| 英文摘要 | four new cyclic peptides, brachystemins f-i (1-4), and 11 known compounds were isolated from the aerial parts of brachystemma calycinim. the absolute configurations of compounds 1-4 were assigned using marfey's method. the structure of compound 5 was revised from cyclo-(pro(1)-phe(2)-leu(3)-ala(4)-thr(5)-pro(6)-ala(7)-gly(8)) to cyclo-(pro(1)-pro(2)-ala(3)-gly(4)-leu(5)-ala(6)-thr(7)-phe(8)) with qtof/ms and x-ray diffraction analysis. the n-containing compounds were assessed for their inhibitory effects on the secretion of monocyte chemokine ligand 2 (ccl-2), interleukin 6 (il-6), and collagen iv against high-glucose-stimulated mesangial cells. compound 5 was evaluated for its effects on collagen i, reactive oxygen species (ros), superoxide anion (o(2)(center dot-)) production, and cell viability in mesangial cells, and on nitric oxide (no) production in macrophage cells. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 学科主题 | 物理化学 |
| 类目[WOS] | plant sciences ; chemistry, medicinal ; pharmacology & pharmacy |
| 研究领域[WOS] | plant sciences ; pharmacology & pharmacy |
| 关键词[WOS] | diabetic-nephropathy ; inflammation ; expression ; alkaloids ; collagen ; glucose ; alpha ; beta |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000291920600007 |
| 公开日期 | 2012-07-09 |
| 源URL | [http://159.226.238.44/handle/321008/115829]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.So Med Univ, Nanfang Hosp, Div Nephrol, Key Lab Organ Failure Res,Educ Minist, Guangzhou 510515, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.Chengdu Univ Tradit Chinese Med, Coll Pharm, Chengdu 610075, Peoples R China 4.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Jun,Zhou, Li-Li,Li, Xi,et al. Bioactive Compounds from the Aerial Parts of Brachystemma calycinum and Structural Revision of an Octacyclopeptide[J]. journal of natural products,2011,74(6):1392-1400. |
| APA | Zhao, Jun,Zhou, Li-Li,Li, Xi,Xiao, Hong-Bin,Hou, Fan-Fan,&Cheng, Yong-Xian.(2011).Bioactive Compounds from the Aerial Parts of Brachystemma calycinum and Structural Revision of an Octacyclopeptide.journal of natural products,74(6),1392-1400. |
| MLA | Zhao, Jun,et al."Bioactive Compounds from the Aerial Parts of Brachystemma calycinum and Structural Revision of an Octacyclopeptide".journal of natural products 74.6(2011):1392-1400. |
入库方式： OAI收割
来源：大连化学物理研究所
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