Bioactivation of herbal constituents: simple alerts in the complex system
文献类型：期刊论文
| 作者 | Fang, Zhong-Ze1,2; Zhang, Yan-Yan1; Wang, Xiu-Li1; Cao, Yun-Feng1; Huo, Hong1; Yang, Ling1 |
| 刊名 | expert opinion on drug metabolism & toxicology
 |
| 出版日期 | 2011-08-01 |
| 卷号 | 7期号:8页码:989-1007 |
| 关键词 | bioactivation herbal medicines herbal toxicity herb-drug interactions |
| ISSN号 | 待补充 |
| 产权排序 | 1,1 |
| 通讯作者 | 杨凌 |
| 中文摘要 | bioactivation of herbal constituents: simple alerts in the complex system |
| 英文摘要 | introduction: the elucidation of the toxicological mechanisms of herbal medicines is becoming more and more important with the increasing application of herbal medicines, for treatment of various diseases and the promotion of health. furthermore, it is widely recognized that as herbal components undergo bioactivation, there is a critical need for a greater understanding of herbal toxicity induction. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 学科主题 | 物理化学 |
| 类目[WOS] | biochemistry & molecular biology ; pharmacology & pharmacy |
| 研究领域[WOS] | biochemistry & molecular biology ; pharmacology & pharmacy |
| 关键词[WOS] | human liver-microsomes ; mechanism-based inactivation ; human cytochrome-p450 enzymes ; pyrrolizidine alkaloid senecionine ; carcinogenic aristolochic acids ; metabolic-activation ; chinese herbs ; in-vitro ; species-differences ; covalent binding |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000292840100005 |
| 公开日期 | 2012-07-09 |
| 源URL | [http://159.226.238.44/handle/321008/115854]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fang, Zhong-Ze,Zhang, Yan-Yan,Wang, Xiu-Li,et al. Bioactivation of herbal constituents: simple alerts in the complex system[J]. expert opinion on drug metabolism & toxicology,2011,7(8):989-1007. |
| APA | Fang, Zhong-Ze,Zhang, Yan-Yan,Wang, Xiu-Li,Cao, Yun-Feng,Huo, Hong,&Yang, Ling.(2011).Bioactivation of herbal constituents: simple alerts in the complex system.expert opinion on drug metabolism & toxicology,7(8),989-1007. |
| MLA | Fang, Zhong-Ze,et al."Bioactivation of herbal constituents: simple alerts in the complex system".expert opinion on drug metabolism & toxicology 7.8(2011):989-1007. |
入库方式： OAI收割
来源：大连化学物理研究所
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