A functional metabolomics platform based on non-target and target chromatography-mass spectrometry
文献类型：会议论文
| 作者 | Xu GW(许国旺) ; Zhao XJ(赵欣捷) ; Hu CX(胡春秀) ; Wang XL(王晓琳) ; Chen SL(陈世礼) ; Li J(李佳) |
| 出版日期 | 2011 |
| 会议名称 | the 2nd asian and oceanic mass spectrometry conference |
| 会议日期 | 2011-8-17 |
| 会议地点 | 釜山 |
| 页码 | 58-0 |
| 通讯作者 | 许国旺 |
| 中文摘要 | recently the detection of biomarkers by targeted and non-targeted metabolomics studies is continuously increasing with a special focus on complicated disease research especially on diagnosis and treatment of metabolic diseases. however, until now the majority of studies are descriptive, only the differences in the relative or absolute contents were reported, very few dealt with the function of differential metabolites, most of the explanation on the function of the detected so-called biomarkers, if there was, was based on the literatures. in this lecture, we shall report a functional metabolomics platform including tissue-specific cell culture with isotope-labelled compounds, target and non-target analyses based on the var-ious chromatography - mass spectrometry methods and multi-variable analysis data analysis. the prediabete and exercise studies will be used as the examples to show the usefulness of our platform. it is expected that the functional metabolomics study will improve current knowledge on the regulation of metabolic processes in health and disease states, it is helpful to find new therapeutic targets for diseases. |
| 合作状况 | 分会特邀报告 |
| 会议主办者 | korean society for mass spectrometry |
| 会议录 | 2011 annual meeting of ksms & 2nd aomsc
 |
| 会议录出版者 | 待补充 |
| 学科主题 | 分析化学 |
| 会议录出版地 | 待补充 |
| 源URL | [http://159.226.238.44/handle/321008/116059]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 推荐引用方式 GB/T 7714 | Xu GW,Zhao XJ,Hu CX,et al. A functional metabolomics platform based on non-target and target chromatography-mass spectrometry[C]. 见:the 2nd asian and oceanic mass spectrometry conference. 釜山. 2011-8-17. |
入库方式： OAI收割
来源：大连化学物理研究所
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