New Chalcone and Dimeric Chalcones with 1,4-p-Benzoquinone Residue from Combretum yunnanense
文献类型：期刊论文
| 作者 | Wu, Ming-Mei1,2; Wang, Li-Qin1; Hua, Yan2; Chen, Ye-Gao1; Wang, Yuan-Yuan3; Li, Xing-Yao3; Li, Yan3 ; Li, Ting1; Yang, Xun-Yun1; Tang, Zheng-Rong1
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| 刊名 | PLANTA MEDICA
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| 出版日期 | 2011-03-01 |
| 卷号 | 77期号:5页码:481-484 |
| 关键词 | Combretum yunnanense Combretaceae combrequinone A combrequinone B combrequinone C cytotoxicity |
| ISSN号 | 0032-0943 |
| 通讯作者 | Wang, LQ (reprint author), Yunnan Normal Univ, Dept Chem & Chem Engn, 121 St, Kunming 650051, Yunnan, Peoples R China |
| 英文摘要 | New chalcone and dimeric chalcones with 1,4-p-benzoquinone residue, combrequinone A (1), combrequinone B (2), and combrequinone C (3), along with three known compounds (4-6), were isolated from the ethanolic extract of the stems and leaves of Combretum yunnanense, and their structures were determined by spectroscopic analysis. Compounds 1-3 were evaluated for in vitro cytotoxicity against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7, and SW480. Compounds 1, 2, and 3 were found to be most potent against HL-60 acute leukemia cells, with IC(50) values of 4.63, 4.07, and 1.26 mu M, respectively. |
| 学科主题 | Plant Sciences; Pharmacology & Pharmacy |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | CONSTITUENTS ; AGENTS |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundations of China[20802064]; Natural Science Foundations of Yunnan Province[2007B200 M] |
| 语种 | 英语 |
| WOS记录号 | WOS:000288847600012 |
| 公开日期 | 2012-07-18 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/13565]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Yunnan Normal Univ, Dept Chem & Chem Engn, Kunming 650051, Yunnan, Peoples R China 2.SW Forestry Univ, Dept Nat Sources, Kunming, Yunnan, Peoples R China 3.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Drug Screening Ctr, Kunming, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Ming-Mei,Wang, Li-Qin,Hua, Yan,et al. New Chalcone and Dimeric Chalcones with 1,4-p-Benzoquinone Residue from Combretum yunnanense[J]. PLANTA MEDICA,2011,77(5):481-484. |
| APA | Wu, Ming-Mei.,Wang, Li-Qin.,Hua, Yan.,Chen, Ye-Gao.,Wang, Yuan-Yuan.,...&Tang, Zheng-Rong.(2011).New Chalcone and Dimeric Chalcones with 1,4-p-Benzoquinone Residue from Combretum yunnanense.PLANTA MEDICA,77(5),481-484. |
| MLA | Wu, Ming-Mei,et al."New Chalcone and Dimeric Chalcones with 1,4-p-Benzoquinone Residue from Combretum yunnanense".PLANTA MEDICA 77.5(2011):481-484. |
入库方式： OAI收割
来源：昆明植物研究所
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