Antiproliferative Diterpenoids from the Leaves of Isodon rubescens
文献类型：期刊论文
| 作者 | Gao, Xue-Mei1,4; Luo, Xiao1; Pu, Jian-Xin1 ; Wu, Ying-Li2,3; Zhao, Yong1; Yang, Li Bin1; He, Fei1; Li, Xiao Nian1; Xiao, Wei-Lie1; Chen, Guo-Qiang2,3
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| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2011 |
| 卷号 | 77期号:2页码:169-174 |
| 关键词 | Isodon rubescens Labiatae cytotoxicity diterpenoid |
| ISSN号 | 0032-0943 |
| 通讯作者 | Sun, HD (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Lan Hei Rd, Kunming 650204, Yunnan, Peoples R China |
| 英文摘要 | A phytochemical study of Isodon rubescens leaves led to the isolation of five new diterpenoids, isorubesins A-E (1 - 5), and fifteen known diterpenoids. The structures of these new compounds were elucidated by spectroscopic evidence. Most of the diterpenoids were tested for cytotoxicity against NB4, A549, SHSY5Y, PC3, and MCF7 human tumor cells. Some of them showed potent inhibitory activity. Compound 5 is the first reported atisane-type diterpenoid from this plant. |
| 学科主题 | Plant Sciences; Pharmacology & Pharmacy |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | ENT-KAURANE DITERPENOIDS ; VAR.-RUBESCENS ; KAURENE DITERPENOIDS ; A-C ; PARVIFOLIUS |
| 收录类别 | SCI |
| 资助信息 | NSFC[30772637]; NSFC-Joint Foundation of Yunnan Province[U0832602]; Major State Basic Research Development Program of China[2009CB522300]; Natural Science Foundation of Yunnan Province[2008CD162]; CAS[KSCX2-YW-R-097] |
| 语种 | 英语 |
| WOS记录号 | WOS:000286461000012 |
| 公开日期 | 2012-07-18 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/13575]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Shanghai Jiao Tong Univ, Sch Med, Dept Pathophysiol, Shanghai 200030, Peoples R China 3.Shanghai Jiao Tong Univ, Sch Med, Key Lab Cell Differentiat & Apoptosis, Chinese Minist Educ, Shanghai 200030, Peoples R China 4.Yunnan Nationalities Univ, Sch Chem & Biotechnol, Kunming 650031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, Xue-Mei,Luo, Xiao,Pu, Jian-Xin,et al. Antiproliferative Diterpenoids from the Leaves of Isodon rubescens[J]. PLANTA MEDICA,2011,77(2):169-174. |
| APA | Gao, Xue-Mei.,Luo, Xiao.,Pu, Jian-Xin.,Wu, Ying-Li.,Zhao, Yong.,...&Sun, Han-Dong.(2011).Antiproliferative Diterpenoids from the Leaves of Isodon rubescens.PLANTA MEDICA,77(2),169-174. |
| MLA | Gao, Xue-Mei,et al."Antiproliferative Diterpenoids from the Leaves of Isodon rubescens".PLANTA MEDICA 77.2(2011):169-174. |
入库方式： OAI收割
来源：昆明植物研究所
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