Neoclerodane Diterpenoids from Scutellaria barbata
文献类型：期刊论文
| 作者 | Zhu, Feng1,2; Di, Ying-Tong1 ; Li, Xing-Yao1; Liu, Ling-Li1; Zhang, Qiang1; Li, Yan1; Hao, Xiao-Jiang1; He, Hong-Ping1
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| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2011-09-01 |
| 卷号 | 77期号:13页码:1536-1541 |
| 关键词 | Scutellaria barbata Lamiaceae neoclerodane diterpenoids scutebatas H-O cytotoxicity |
| ISSN号 | 0032-0943 |
| 通讯作者 | He, HP (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, 132 Lanhei Rd, Kunming 650204, Yunnan, Peoples R China |
| 英文摘要 | Eight new neoclerodane diterpenoids (1-8), scutebatas H-O, together with eight known compounds, have been isolated from the whole plant of Scutellaria barbata D. Don. Their structures were elucidated on the basis of spectroscopic studies. In vitro cytotoxicity of selected compounds against cancer cell lines HL-60, SMMC-7721, A-549, MCF-7, and SW480 was evaluated. Compounds 5, 6, 7 showed moderate cytotoxicities against several human cancer cell lines, with IC(50) values ranging from 12.6-31.4 mu M. In addition, compound 1 showed selective cytotoxicity against MCF-7. |
| 学科主题 | Plant Sciences; Pharmacology & Pharmacy |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | CYTOTOXIC ACTIVITIES ; CANCER ; CELLS ; EXTRACT |
| 收录类别 | SCI |
| 资助信息 | Ministry of Science and Technology of China[2009CB940900, 2009CB522300]; Foundation of the Chinese Academy of Sciences; Young Academic and Technical Leader Raising Foundation of Yunnan Province[2010CI047] |
| 语种 | 英语 |
| WOS记录号 | WOS:000294481300013 |
| 公开日期 | 2012-07-18 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/13577]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Feng,Di, Ying-Tong,Li, Xing-Yao,et al. Neoclerodane Diterpenoids from Scutellaria barbata[J]. PLANTA MEDICA,2011,77(13):1536-1541. |
| APA | Zhu, Feng.,Di, Ying-Tong.,Li, Xing-Yao.,Liu, Ling-Li.,Zhang, Qiang.,...&He, Hong-Ping.(2011).Neoclerodane Diterpenoids from Scutellaria barbata.PLANTA MEDICA,77(13),1536-1541. |
| MLA | Zhu, Feng,et al."Neoclerodane Diterpenoids from Scutellaria barbata".PLANTA MEDICA 77.13(2011):1536-1541. |
入库方式： OAI收割
来源：昆明植物研究所
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