Cytotoxic diterpenoids from Isodon enanderianus
文献类型：期刊论文
| 作者 | Xiang, W; Na, Z; Li, SH ; Li, ML; Li, RT; Tian, QE; Sun, HD
|
| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2003-11-01 |
| 卷号 | 69期号:11页码:1031-1035 |
| 关键词 | Isodon enanderianus Labiatae diterpenoids ent-kaurane ent-abietane enanderianins K-P cytotoxicity |
| ISSN号 | 0032-0943 |
| 英文摘要 | Five new ent-kaurane diterpenoids, enanderianins K-O (1-5), and one new ent-abietane diterpenoid, enanderianin P (6), together with five known ent-kaurane diterpenoids, rabdocoetsin A (7), rabdocoetsin B (8), rabdocoetsin D (9), megathyrin A (10), megathyrin B (11) were isolated from the aerial parts of Isodon enanderianus. Their structures were determined by spectral means. Some diterpenoids were tested for their cytotoxicity against the human tumor K562 cells. Compounds 1, 2, 6, 8, 9 showed significant inhibitory activities against K562 cells with IC50 values ranging from 0.13 to 0.87 mug/mL. |
| 学科主题 | Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | ENT-KAURANE DITERPENOIDS ; ERIOCALYX VAR. LAXIFLORA ; MEGATHYRSUS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000187741500012 |
| 公开日期 | 2012-07-18 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/13631]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Kunming Med Coll, Yunnan Phatmacol Lab Nat Prod, Kunming, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xiang, W,Na, Z,Li, SH,et al. Cytotoxic diterpenoids from Isodon enanderianus[J]. PLANTA MEDICA,2003,69(11):1031-1035. |
| APA | Xiang, W.,Na, Z.,Li, SH.,Li, ML.,Li, RT.,...&Sun, HD.(2003).Cytotoxic diterpenoids from Isodon enanderianus.PLANTA MEDICA,69(11),1031-1035. |
| MLA | Xiang, W,et al."Cytotoxic diterpenoids from Isodon enanderianus".PLANTA MEDICA 69.11(2003):1031-1035. |
入库方式： OAI收割
来源：昆明植物研究所
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