Studies on the synthesis of novel chalcone and biological activity
文献类型：期刊论文
| 作者 | Liao, TG; Wang, QA; Fang, WQ; Zhu, HJ |
| 刊名 | CHINESE JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2006-05-01 |
| 卷号 | 26期号:5页码:685-689 |
| 关键词 | hydroxylated chalcone farnesyloxy chalcone prenyloxy chalcone synthesis biological activity |
| 英文摘要 | Eight novel chalcone compounds 1a similar to 1h were synthesized by esterification, methoxymethyl protection or methylation, hydrazidation, oxidation, aldol condensation, deprotection, O-farnesylation or O-prenylation respectively using 3,5-dihydroxybenzoic acid as starting material in overall yields of 5.6%similar to 46%. Their structures were confirmed by H-1 NMR, C-13 NMR, IR and MS spectra. Target compounds were screened with three international standard models for biological activity. Results showed that 1b against model CAT-B and le against model CDC25 possessed the good inhibition activity. |
| 学科主题 | Chemistry, Organic |
| 类目[WOS] | Chemistry, Organic |
| 研究领域[WOS] | Chemistry |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000237683900015 |
| 公开日期 | 2012-07-18 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/13747]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Hunan Univ, Coll Chem & Chem Engn, Changsha 410082, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Photochem & Plant Resource W China, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liao, TG,Wang, QA,Fang, WQ,et al. Studies on the synthesis of novel chalcone and biological activity[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2006,26(5):685-689. |
| APA | Liao, TG,Wang, QA,Fang, WQ,&Zhu, HJ.(2006).Studies on the synthesis of novel chalcone and biological activity.CHINESE JOURNAL OF ORGANIC CHEMISTRY,26(5),685-689. |
| MLA | Liao, TG,et al."Studies on the synthesis of novel chalcone and biological activity".CHINESE JOURNAL OF ORGANIC CHEMISTRY 26.5(2006):685-689. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。