Chemical constituents of the suspension cell cultures of Maytenus hookeri
文献类型：期刊论文
| 作者 | Lu, CH; Zhang, JX; Gan, FY; Shen, YM |
| 刊名 | ACTA BOTANICA SINICA
 |
| 出版日期 | 2002-05-01 |
| 卷号 | 44期号:5页码:603-610 |
| 关键词 | Maytenus hookeri Celastraceae suspension cell cultures maytansine 2 3-diacetoxyl maytenusone |
| ISSN号 | 0577-7496 |
| 英文摘要 | Suspension cell cultures of Maytenus hookeri Loos. (Celastraceae) in SH media were established from the calli induced from the leaves and young steins of M. hookeri on MS media with the supplement of 2 mg/L 2,4-D and 0.1 mg/L KIN (kinetin). Ethyl acetate extract of the cultures showed inhibitory activities against Penicillium avellaneum UC-4376 which was sensitive to maytansinoids. Exhaustive isolation of natural products from a large scale of suspension cell cultures did not yield maytansine instead of affording nine compounds including one novel triterpenoid, named 2, 3-diacetoxyl maytenusone (1), and eight known ones including squalene (2), beta-sitosterol (3), 2', 3', 4-triacetyl-sitoindoside I (4), salaspermic acid (5), maytenonic acid (6), 2alpha-hydroxy-maytenonic acid (7), 6, 11,12-trihydroxy-8, 11, 13-abietrien-7-one (8) and 11, 12-dihydroxy-8, 11, 13-abietatrien-7-one (9) elucidated on the basis of 1D and 2D NMR data. The H-1-NMR and C-13-NMR assignments were made for 1, 5, 6 and 7, while the C-13-NMR assignments for 5 and 6 were revised. The chemical results suggested that the suspension cell cultures of M. hookeri did not produce maytansinoids under the reported experiment conditions. |
| 学科主题 | Biochemistry & Molecular Biology; Plant Sciences |
| 类目[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 关键词[WOS] | TRIPTERYGIUM-WILFORDII ; SALASPERMIC ACID ; TRITERPENES ; DITERPENOIDS ; CANARIENSIS ; ANSAMITOCIN ; INHIBITORS ; AGENTS ; ROOTS ; P-3 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000175739000018 |
| 公开日期 | 2012-07-24 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/14211]  |
| 专题 | 昆明植物研究所_离退休 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Key Lab Nat Prod Chem Guizhou Prov, Guiyang 550002, Peoples R China 3.Acad Sinica, Guiyang 550002, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lu, CH,Zhang, JX,Gan, FY,et al. Chemical constituents of the suspension cell cultures of Maytenus hookeri[J]. ACTA BOTANICA SINICA,2002,44(5):603-610. |
| APA | Lu, CH,Zhang, JX,Gan, FY,&Shen, YM.(2002).Chemical constituents of the suspension cell cultures of Maytenus hookeri.ACTA BOTANICA SINICA,44(5),603-610. |
| MLA | Lu, CH,et al."Chemical constituents of the suspension cell cultures of Maytenus hookeri".ACTA BOTANICA SINICA 44.5(2002):603-610. |
入库方式： OAI收割
来源：昆明植物研究所
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